Enzyme

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     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.11 With incorporation of two atoms of oxygen
ID:1.13.11.58
Description:Linoleate 9S-lipoxygenase.
Alternative Name: Linoleate 9-lipoxygenase.
9S-lipoxygenase.
9-lipoxygenase.
Cath: 1.20.245.10; 3.10.450.60; 4.10.372.10; 4.10.375.10; 2.60.60.20;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.11.58
BRENDA Enzyme Link: BRENDA 1.13.11.58
KEGG Enzyme Link: KEGG1.13.11.58
BioCyc Enzyme Link: BioCyc 1.13.11.58
ExPASy Enzyme Link: ExPASy1.13.11.58
EC2PDB Enzyme Link: EC2PDB 1.13.11.58
ExplorEnz Enzyme Link: ExplorEnz 1.13.11.58
PRIAM enzyme-specific profiles Link: PRIAM 1.13.11.58
IntEnz Enzyme Link: IntEnz 1.13.11.58
MEDLINE Enzyme Link: MEDLINE 1.13.11.58
MSA:

1.13.11.58;

Phylogenetic Tree:

1.13.11.58;

Uniprot:
M-CSA:
RHEA:30291 (9Z,12Z)-octadecadienoate + O2 = (9S)-hydroperoxy-(10E,12Z)-octadecadienoate
RULE(radius=1) [*:1]-[CH;+0:2]=[CH;+0:3]-[CH2;+0:4]-[*:5].[O;H0;+0:6]=[O;H0;+0:7]>>[*:1]-[CH;+0:2](-[CH;+0:3]=[CH;+0:4]-[*:5])-[O;H0;+0:6]-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid.Wennman A, Jernerén F, Magnuson A, Oliw EH2015 Oct 126264916
Secretion of two novel enzymes, manganese 9S-lipoxygenase and epoxy alcohol synthase, by the rice pathogen Magnaporthe salvinii.Wennman A, Oliw EH2013 Mar23233731
Molecular cloning and functional expression of a phorbol ester-inducible 8S-lipoxygenase from mouse skin.Jisaka M, Kim RB, Boeglin WE, Nanney LB, Brash AR1997 Sep 269305900
Expression of lipoxygenase in wounded tubers of Solanum tuberosum L.Geerts A, Feltkamp D, Rosahl S1994 May8029354
On the substrate binding of linoleate 9-lipoxygenases.Andreou AZ, Hornung E, Kunze S, Rosahl S, Feussner I2009 Mar19037675
Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.Bannenberg G, Martínez M, Hamberg M, Castresana C2009 Feb18949503
Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases.Boeglin WE, Itoh A, Zheng Y, Coffa G, Howe GA, Brash AR2008 Nov18795358
Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade.Vellosillo T, Martínez M, López MA, Vicente J, Cascón T, Dolan L, Hamberg M, Castresana C2007 Mar17369372
Characterization of three potato lipoxygenases with distinct enzymatic activities and different organ-specific and wound-regulated expression patterns.Royo J, Vancanneyt G, Pérez AG, Sanz C, Störmann K, Rosahl S, Sánchez-Serrano JJ1996 Aug 308702864