EC number:1.13.11.60

Enzyme

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EC Tree
     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.11 With incorporation of two atoms of oxygen
ID:1.13.11.60
Description:Linoleate 8R-lipoxygenase.
Alternative Name: 7,8-linoleate diol synthase (bifunctional enzyme).
5,8-linoleate diol synthase (bifunctional enzyme).

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.11.60
BRENDA Enzyme Link: BRENDA 1.13.11.60
KEGG Enzyme Link: KEGG1.13.11.60
BioCyc Enzyme Link: BioCyc 1.13.11.60
ExPASy Enzyme Link: ExPASy1.13.11.60
EC2PDB Enzyme Link: EC2PDB 1.13.11.60
ExplorEnz Enzyme Link: ExplorEnz 1.13.11.60
PRIAM enzyme-specific profiles Link: PRIAM 1.13.11.60
IntEnz Enzyme Link: IntEnz 1.13.11.60
MEDLINE Enzyme Link: MEDLINE 1.13.11.60

EC number:1.13.11.60

MSA:

1.13.11.60;
Phylogenetic Tree:

1.13.11.60;
Uniprot:
M-CSA:
RHEA:25395 (9Z,12Z)-octadecadienoate + O2 = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification of PpoA from Aspergillus nidulans as a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450.Brodhun F, Göbel C, Hornung E, Feussner I2009 May 119286665
Pichia expression and mutagenesis of 7,8-linoleate diol synthase change the dioxygenase and hydroperoxide isomerase.Garscha U, Oliw E2008 Sep 518586008