EC number:1.13.11.72
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.11 With incorporation of two atoms of oxygen |
| ID: | 1.13.11.72 |
|---|---|
| Description: | 2-hydroxyethylphosphonate dioxygenase. |
| Alternative Name: |
HEPD. |
| Cath: | 1.10.260.40; 2.60.120.10; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.13.11.72 |
| BRENDA Enzyme Link: | BRENDA 1.13.11.72 |
| KEGG Enzyme Link: | KEGG1.13.11.72 |
| BioCyc Enzyme Link: | BioCyc 1.13.11.72 |
| ExPASy Enzyme Link: | ExPASy1.13.11.72 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.11.72 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.72 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.72 |
| IntEnz Enzyme Link: | IntEnz 1.13.11.72 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.11.72 |
EC number:1.13.11.72
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:34791 | 2-hydroxyethylphosphonate + O2 = formate + H(+) + hydroxymethylphosphonate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[OH;+0:4].[O;H0;+0:5]=[O;H0;+0:6]>>[*:1]-[CH2;+0:2]-[OH;+0:5].[O;H0;+0:4]=[CH;+0:3]-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase. | Peck SC, Cooke HA, Cicchillo RM, Malova P, Hammerschmidt F, Nair SK, van der Donk WA | 2011 Aug 2 | 21711001 |
| On the stereochemistry of 2-hydroxyethylphosphonate dioxygenase. | Whitteck JT, Malova P, Peck SC, Cicchillo RM, Hammerschmidt F, van der Donk WA | 2011 Mar 30 | 21381767 |
| Hydroperoxylation by hydroxyethylphosphonate dioxygenase. | Whitteck JT, Cicchillo RM, van der Donk WA | 2009 Nov 11 | 19839620 |
| An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis. | Cicchillo RM, Zhang H, Blodgett JA, Whitteck JT, Li G, Nair SK, van der Donk WA, Metcalf WW | 2009 Jun 11 | 19516340 |