EC number:1.13.11.78
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.11 With incorporation of two atoms of oxygen |
| ID: | 1.13.11.78 |
|---|---|
| Description: | 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming). |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.13.11.78 |
| BRENDA Enzyme Link: | BRENDA 1.13.11.78 |
| KEGG Enzyme Link: | KEGG1.13.11.78 |
| BioCyc Enzyme Link: | BioCyc 1.13.11.78 |
| ExPASy Enzyme Link: | ExPASy1.13.11.78 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.11.78 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.78 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.78 |
| IntEnz Enzyme Link: | IntEnz 1.13.11.78 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.11.78 |
EC number:1.13.11.78
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:41444 | (2R)-(2-amino-1-hydroxyethyl)phosphonate + O2 = glycine + 2 H(+) + phosphate |
| RULE(radius=1) | [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[CH;+0:5](-[*:6])-[OH;+0:7].[O;H0;+0:8]=[O;H0;+0:9]>>[*:6]-[C;H0;+0:5](=[O;H0;+0:7])-[OH;+0:8].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:9] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases. | Wörsdörfer B, Lingaraju M, Yennawar NH, Boal AK, Krebs C, Bollinger JM Jr, Pandelia ME | 2013 Nov 19 | 24198335 |
| PhnY and PhnZ comprise a new oxidative pathway for enzymatic cleavage of a carbon-phosphorus bond. | McSorley FR, Wyatt PB, Martinez A, DeLong EF, Hove-Jensen B, Zechel DL | 2012 May 23 | 22564006 |
| Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates. | van Staalduinen LM, McSorley FR, Schiessl K, Séguin J, Wyatt PB, Hammerschmidt F, Zechel DL, Jia Z | 2014 Apr 8 | 24706911 |