EC number:1.13.11.85
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.11 With incorporation of two atoms of oxygen |
| ID: | 1.13.11.85 |
|---|---|
| Description: | Exo-cleaving rubber dioxygenase. |
| Alternative Name: |
Heme-dependent rubber oxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.13.11.85 |
| BRENDA Enzyme Link: | BRENDA 1.13.11.85 |
| KEGG Enzyme Link: | KEGG1.13.11.85 |
| BioCyc Enzyme Link: | BioCyc 1.13.11.85 |
| ExPASy Enzyme Link: | ExPASy1.13.11.85 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.11.85 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.85 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.85 |
| IntEnz Enzyme Link: | IntEnz 1.13.11.85 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.11.85 |
EC number:1.13.11.85
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:55920 | [cis-1,4-isoprene](n) + O2 = (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal + cis-1,4-isoprene(n-3) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[CH2;+0:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH3;+0:8])=[CH;+0:9]-[*:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-[*:15]-[CH2;+0:16]-[C;H0;+0:17](=[*:18])-[*:19].[O;H0;+0:20]=[O;H0;+0:21]>>[*:1]-[C;H0;+0:2](-[CH2;+0:9]-[*:10]-[CH;+0:11]=[C;H0;+0:12](-[*:13])-[CH2;+0:14]-[*:15]-[CH;+0:16]=[O;H0;+0:20])=[CH;+0:3]-[*:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:21].[*:18]=[C;H0;+0:17](-[*:19])-[CH3;+0:8] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Rubber oxygenase and latex clearing protein cleave rubber to different products and use different cleavage mechanisms. | Birke J, Jendrossek D | 2014 Aug | 24907333 |
| Structure of the processive rubber oxygenase RoxA from Xanthomonas sp. | Seidel J, Schmitt G, Hoffmann M, Jendrossek D, Einsle O | 2013 Aug 20 | 23922395 |
| Heme-dependent rubber oxygenase RoxA of Xanthomonas sp. cleaves the carbon backbone of poly(cis-1,4-Isoprene) by a dioxygenase mechanism. | Braaz R, Armbruster W, Jendrossek D | 2005 May | 15870336 |
| Novel type of heme-dependent oxygenase catalyzes oxidative cleavage of rubber (poly-cis-1,4-isoprene). | Braaz R, Fischer P, Jendrossek D | 2004 Dec | 15574940 |
| Sequence analysis of a gene product synthesized by Xanthomonas sp. during growth on natural rubber latex. | Jendrossek D, Reinhardt S | 2003 Jul 15 | 12855168 |