EnzyMine

Download

EC Tree

1. Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.11 With incorporation of two atoms of oxygen

ID:	1.13.11.9
Description:	2,5-dihydroxypyridine 5,6-dioxygenase.
Alternative Name:	Pyridine-2,5-diol dioxygenase. 2,5-dihydroxypyridine oxygenase.

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

PDB	Click once to unfold,double click to fold.

UniProtKB Enzyme Link:	UniProtKB 1.13.11.9
BRENDA Enzyme Link:	BRENDA 1.13.11.9
KEGG Enzyme Link:	KEGG1.13.11.9
BioCyc Enzyme Link:	BioCyc 1.13.11.9
ExPASy Enzyme Link:	ExPASy1.13.11.9
EC2PDB Enzyme Link:	EC2PDB 1.13.11.9
ExplorEnz Enzyme Link:	ExplorEnz 1.13.11.9
PRIAM enzyme-specific profiles Link:	PRIAM 1.13.11.9
IntEnz Enzyme Link:	IntEnz 1.13.11.9
MEDLINE Enzyme Link:	MEDLINE 1.13.11.9

RHEA:27522	2,5-dihydroxypyridine + O2 = H(+) + N-formylmaleamate
RULE(radius=1)	[O;H0;+0:1]=[O;H0;+0:2].[OH;+0:3]-[c;H0;+0:4]1:[cH;+0:5]:[cH;+0:6]:[c;H0;+0:7](-[OH;+0:8]):[cH;+0:9]:[n;H0;+0:10]:1>>[O;H0;+0:3]=[C;H0;+0:4](-[CH;+0:5]=[CH;+0:6]-[C;H0;+0:7](=[O;H0;+0:8])-[OH;+0:1])-[NH;+0:10]-[CH;+0:9]=[O;H0;+0:2]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
The metabolism of nicotinic acid. II. 2,5-dihydroxypyridine oxidation, product formation, and oxygen 18 incorporation.	Gauthier JJ, Rittenberg SC	1971 Jun 10	5578918
The metabolism of nicotinic acid. I. Purification and properties of 2,5-dihydroxypyridine oxygenase from Pseudomonas putida N-9.	Gauthier JJ, Rittenberg SC	1971 Jun 10	5578917
Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.	Jiménez JI, Canales A, Jiménez-Barbero J, Ginalski K, Rychlewski L, García JL, Díaz E	2008 Aug 12	18678916