| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) |
| ID: | 1.13.12.21 |
|---|---|
| Description: | Tetracenomycin-F1 monooxygenase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.13.12.21 |
| BRENDA Enzyme Link: | BRENDA 1.13.12.21 |
| KEGG Enzyme Link: | KEGG1.13.12.21 |
| BioCyc Enzyme Link: | BioCyc 1.13.12.21 |
| ExPASy Enzyme Link: | ExPASy1.13.12.21 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.12.21 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.12.21 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.12.21 |
| IntEnz Enzyme Link: | IntEnz 1.13.12.21 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.12.21 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:37447 | O2 + tetracenomycin F1 = H(+) + H2O + tetracenomycin D3 |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[OH2;+0:5] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Tetracenomycin F1 monooxygenase: oxidation of a naphthacenone to a naphthacenequinone in the biosynthesis of tetracenomycin C in Streptomyces glaucescens. | Shen B, Hutchinson CR | 1993 Jul 6 | 8329392 |