EC number:1.13.12.24
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) |
| ID: | 1.13.12.24 |
|---|---|
| Description: | Calcium-regulated photoprotein. |
| Alternative Name: |
Vialidin. Obelin. Mnemiopsin. Mitrocomin. Halistaurin. Clytin. Calcium-activated photoprotein. Ca(2+)-regulated photoprotein. Berovin. Aequorin. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.13.12.24 |
| BRENDA Enzyme Link: | BRENDA 1.13.12.24 |
| KEGG Enzyme Link: | KEGG1.13.12.24 |
| BioCyc Enzyme Link: | BioCyc 1.13.12.24 |
| ExPASy Enzyme Link: | ExPASy1.13.12.24 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.12.24 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.12.24 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.12.24 |
| IntEnz Enzyme Link: | IntEnz 1.13.12.24 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.12.24 |
EC number:1.13.12.24
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:24960 | apo-[aequorin] + 3 Ca(2+) + coelenterazine + O2 = [excited state blue fluorescent protein] + CO2 |
| RULE(radius=1) | [*:1]=[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[n;H0;+0:5]:[c;H0;+0:6]2:[*:7]:[nH;+0:8]:[*:9]:[*:10]:[n;H0;+0:11]:1-2.[O;H0;+0:12]=[O;H0;+0:13]>>[*:4]-[C;H0;+0:3](=[O;H0;+0:12])-[NH;+0:5]-[c;H0;+0:6]1:[*:7]:[n;H0;+0:8]:[*:9]:[*:10]:[n;H0;+0:11]:1.[*:1]=[C;H0;+0:2]=[O;H0;+0:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Intermolecular energy transfer in the bioluminescent system of Aequorea. | Morise H, Shimomura O, Johnson FH, Winant J | 1974 Jun 4 | 4151620 |
| Cloning and sequence analysis of cDNA for the luminescent protein aequorin. | Inouye S, Noguchi M, Sakaki Y, Takagi Y, Miyata T, Iwanaga S, Miyata T, Tsuji FI | 1985 May | 3858813 |
| All three Ca2+-binding loops of photoproteins bind calcium ions: the crystal structures of calcium-loaded apo-aequorin and apo-obelin. | Deng L, Vysotski ES, Markova SV, Liu ZJ, Lee J, Rose J, Wang BC | 2005 Mar | 15689515 |
| The crystal structure of the photoprotein aequorin at 2.3 A resolution. | Head JF, Inouye S, Teranishi K, Shimomura O | 2000 May 18 | 10830969 |