| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) |
| ID: | 1.13.12.4 | ||
|---|---|---|---|
| Description: | Lactate 2-monooxygenase. | ||
| Alternative Name: |
Lactate oxygenase. Lactate oxidative decarboxylase. Lactate oxidase. | ||
| Prosite: | PDOC00482; | ||
| PDB: |
|
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.13.12.4 |
| BRENDA Enzyme Link: | BRENDA 1.13.12.4 |
| KEGG Enzyme Link: | KEGG1.13.12.4 |
| BioCyc Enzyme Link: | BioCyc 1.13.12.4 |
| ExPASy Enzyme Link: | ExPASy1.13.12.4 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.12.4 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.12.4 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.12.4 |
| IntEnz Enzyme Link: | IntEnz 1.13.12.4 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.12.4 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:16513 | (S)-lactate + O2 = acetate + CO2 + H2O |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6].[O;H0;+0:7]=[O;H0;+0:8]>>[*:5]-[C;H0;+0:4](-[*:6])=[O;H0;+0:7].[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[OH2;+0:8] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mechanism of action and crystallization of lactic oxidative decarboxylase from Mycobacterium phlei. | SUTTON WB | 1957 May | 13428772 |
| Cloning and analysis of the L-lactate utilization genes from Streptococcus iniae. | Gibello A, Collins MD, Domínguez L, Fernández-Garayzábal JF, Richardson PT | 1999 Oct | 10508058 |