EC number:1.13.12.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) |
| ID: | 1.13.12.5 |
|---|---|
| Description: | Renilla-type luciferase. |
| Alternative Name: |
Renilla-luciferin 2-monooxygenase. Luciferase. |
| Cath: | 3.40.50.1820; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.13.12.5 |
| BRENDA Enzyme Link: | BRENDA 1.13.12.5 |
| KEGG Enzyme Link: | KEGG1.13.12.5 |
| BioCyc Enzyme Link: | BioCyc 1.13.12.5 |
| ExPASy Enzyme Link: | ExPASy1.13.12.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.12.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.12.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.12.5 |
| IntEnz Enzyme Link: | IntEnz 1.13.12.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.12.5 |
EC number:1.13.12.5
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:14765 | coelenterazine h + O2 = CO2 + excited coelenteramide h monoanion + H(+) + hnu |
| RULE(radius=1) | [*:1]=[c;H0;+0:2]1:[c;H0;+0:3](-[CH2;+0:4]-[c;H0;+0:5](:[*:6]):[cH;+0:7]:[cH;+0:8]:[*:9]):[n;H0;+0:10]:[c;H0;+0:11]2:[*:12]:[nH;+0:13]:[*:14]:[cH;+0:15]:[n;H0;+0:16]:1-2.[O;H0;+0:17]=[O;H0;+0:18]>>[*:1]=[C;H0;+0:2](-[CH2;+0:3]-[c;H0;+0:4](:[cH;+0:5]:[*:6]):[cH;+0:8]:[*:9])-[NH;+0:16]-[c;H0;+0:11]1:[*:12]:[n;H0;+0:13]:[*:14]:[cH;+0:15]:[n;H0;+0:10]:1.[O;H0;+0:17]=[C;H0;+0:7]=[O;H0;+0:18] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Bioluminescence in coelenterates. | Cormier MJ, Hori K, Anderson JM | 1974 Oct 31 | 4154104 |
| Mechanism of calcium induction of Renilla bioluminescence. Involvement of a calcium-triggered luciferin binding protein. | Anderson JM, Charbonneau H, Cormier MJ | 1974 Mar 12 | 4149963 |
| Ca2+-induced bioluminescence in Renilla reniformis. Purification and characterization of a calcium-triggered luciferin-binding protein. | Charbonneau H, Cormier MJ | 1979 Feb 10 | 33174 |
| Renilla luciferin as the substrate for calcium induced photoprotein bioluminescence. Assignment of luciferin tautomers in aequorin and mnemiopsin. | Hori K, Anderson JM, Ward WW, Cormier MJ | 1975 Jun 3 | 237531 |
| Chemical nature of bioluminescence systems in coelenterates. | Shimomura O, Johnson FH | 1975 Apr | 236561 |
| Crystal structures of the luciferase and green fluorescent protein from Renilla reniformis. | Loening AM, Fenn TD, Gambhir SS | 2007 Dec 7 | 17980388 |
| Isolation and expression of a cDNA encoding Renilla reniformis luciferase. | Lorenz WW, McCann RO, Longiaru M, Cormier MJ | 1991 May 15 | 1674607 |