Enzyme

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     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
ID:1.13.12.6
Description:Cypridina-luciferin 2-monooxygenase.
Alternative Name: Luciferase.
Cypridina-type luciferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.12.6
BRENDA Enzyme Link: BRENDA 1.13.12.6
KEGG Enzyme Link: KEGG1.13.12.6
BioCyc Enzyme Link: BioCyc 1.13.12.6
ExPASy Enzyme Link: ExPASy1.13.12.6
EC2PDB Enzyme Link: EC2PDB 1.13.12.6
ExplorEnz Enzyme Link: ExplorEnz 1.13.12.6
PRIAM enzyme-specific profiles Link: PRIAM 1.13.12.6
IntEnz Enzyme Link: IntEnz 1.13.12.6
MEDLINE Enzyme Link: MEDLINE 1.13.12.6
MSA:

1.13.12.6;

Phylogenetic Tree:

1.13.12.6;

Uniprot:
M-CSA:
RHEA:22760 Cypridina luciferin + O2 = CO2 + hnu + oxidized Cypridina luciferin
RULE(radius=1) [*:1]=[c;H0;+0:2]1:[c;H0;+0:3](-[CH;+0:4](-[*:5])-[CH2;+0:6]-[CH3;+0:7]):[n;H0;+0:8]:[c;H0;+0:9]2:[*:10]:[nH;+0:11]:[*:12]:[cH;+0:13]:[n;H0;+0:14]:1-2.[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]=[C;H0;+0:2](-[NH;+0:14]-[c;H0;+0:9]1:[*:10]:[n;H0;+0:11]:[*:12]:[cH;+0:13]:[n;H0;+0:8]:1)-[CH;+0:3](-[CH3;+0:7])-[CH2;+0:4]-[*:5].[O;H0;+0:15]=[C;H0;+0:6]=[O;H0;+0:16]
Reaction
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References

TitleAuthorsDatePubMed ID
Mechanism of the enzyme--catalyzed oxidation of Cypridina and firefly luciferins studied by means of 17O2 and H218O1.Tsuji FI, DeLuca M, Boyer PD, Endo S, Akutagawa M1977 Jan 24836314
Some properties of luciferase from the bioluminescent crustacean, Cypridina hilgendorfii.Tsuji FI, Lynch RV 3rd, Stevens CL1974 Dec 34433517
Cloning and expression of cDNA for the luciferase from the marine ostracod Vargula hilgendorfii.Thompson EM, Nagata S, Tsuji FI1989 Sep2771943