EC number:1.13.12.7

Enzyme

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EC Tree
     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
ID:1.13.12.7
Description:Firefly luciferase.
Alternative Name: Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing).
Photinus pyralis luciferase.
Luciferase.
Prosite: PDOC00427;
PDB:
PDBScop
Cath: 3.30.300.30; 4.10.8.10; 3.40.50.980; 2.30.38.10; 3.40.50.12780;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.12.7
BRENDA Enzyme Link: BRENDA 1.13.12.7
KEGG Enzyme Link: KEGG1.13.12.7
BioCyc Enzyme Link: BioCyc 1.13.12.7
ExPASy Enzyme Link: ExPASy1.13.12.7
EC2PDB Enzyme Link: EC2PDB 1.13.12.7
ExplorEnz Enzyme Link: ExplorEnz 1.13.12.7
PRIAM enzyme-specific profiles Link: PRIAM 1.13.12.7
IntEnz Enzyme Link: IntEnz 1.13.12.7
MEDLINE Enzyme Link: MEDLINE 1.13.12.7

EC number:1.13.12.7

MSA:

1.13.12.7;
Phylogenetic Tree:

1.13.12.7;
Uniprot:
M-CSA:
RHEA:10732 ATP + D-firefly luciferin + O2 = AMP + CO2 + diphosphate + firefly oxyluciferin + hnu
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]=[C;H0;+0:8](-[OH;+0:9])-[CH;+0:10](-[*:11])-[*:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:11]-[C;H0;+0:10](-[*:12])=[O;H0;+0:13].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:14].[*:7]=[C;H0;+0:8]=[O;H0;+0:9]
Reaction
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References

TitleAuthorsDatePubMed ID
Luciferase of Luciola mingrelica fireflies. Kinetics and regulation mechanism.Ugarova NN1989 Jul2801227