EC Tree |
1. Oxidoreductases |
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor |
ID: | 1.14.11.11 | ||
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Description: | Hyoscyamine (6S)-dioxygenase. | ||
Alternative Name: |
Hyoscyamine 6-beta-hydroxylase. Hyoscyamine (6S)-hydroxylase. | ||
Prosite: | PDOC51471; | ||
PDB: |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.14.11.11 |
BRENDA Enzyme Link: | BRENDA 1.14.11.11 |
KEGG Enzyme Link: | KEGG1.14.11.11 |
BioCyc Enzyme Link: | BioCyc 1.14.11.11 |
ExPASy Enzyme Link: | ExPASy1.14.11.11 |
EC2PDB Enzyme Link: | EC2PDB 1.14.11.11 |
ExplorEnz Enzyme Link: | ExplorEnz 1.14.11.11 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.14.11.11 |
IntEnz Enzyme Link: | IntEnz 1.14.11.11 |
MEDLINE Enzyme Link: | MEDLINE 1.14.11.11 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:12629 | 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate |
RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]=[C;H0;+0:5](-[OH;+0:6])-[C;H0;+0:7](=[*:8])-[*:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:10].[*:8]=[C;H0;+0:7](-[*:9])-[OH;+0:11].[*:4]=[C;H0;+0:5]=[O;H0;+0:6] |
Reaction | ![]() |
Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |