| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor |
| ID: | 1.14.11.13 | ||
|---|---|---|---|
| Description: | Gibberellin 2-beta-dioxygenase. | ||
| Alternative Name: |
Gibberellin 2-beta-hydroxylase. | ||
| Prosite: | PDOC51471; | ||
| PDB: |
|
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.11.13 |
| BRENDA Enzyme Link: | BRENDA 1.14.11.13 |
| KEGG Enzyme Link: | KEGG1.14.11.13 |
| BioCyc Enzyme Link: | BioCyc 1.14.11.13 |
| ExPASy Enzyme Link: | ExPASy1.14.11.13 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.11.13 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.11.13 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.11.13 |
| IntEnz Enzyme Link: | IntEnz 1.14.11.13 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.11.13 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:15005 | 2-oxoglutarate + gibberellin A1 + O2 = CO2 + gibberellin A8 + succinate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]=[C;H0;+0:5](-[OH;+0:6])-[C;H0;+0:7](=[*:8])-[*:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:10].[*:8]=[C;H0;+0:7](-[*:9])-[OH;+0:11].[*:4]=[C;H0;+0:5]=[O;H0;+0:6] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genetic analysis reveals that C19-GA 2-oxidation is a major gibberellin inactivation pathway in Arabidopsis. | Rieu I, Eriksson S, Powers SJ, Gong F, Griffiths J, Woolley L, Benlloch R, Nilsson O, Thomas SG, Hedden P, Phillips AL | 2008 Sep | 18805991 |
| Molecular cloning and functional expression of gibberellin 2- oxidases, multifunctional enzymes involved in gibberellin deactivation. | Thomas SG, Phillips AL, Hedden P | 1999 Apr 13 | 10200325 |