EC number:1.14.11.17

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
ID:1.14.11.17
Description:Taurine dioxygenase.
Alternative Name: Alpha-ketoglutarate-dependent taurine dioxygenase.
2-aminoethanesulfonate dioxygenase.
Cath: 3.60.130.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.11.17
BRENDA Enzyme Link: BRENDA 1.14.11.17
KEGG Enzyme Link: KEGG1.14.11.17
BioCyc Enzyme Link: BioCyc 1.14.11.17
ExPASy Enzyme Link: ExPASy1.14.11.17
EC2PDB Enzyme Link: EC2PDB 1.14.11.17
ExplorEnz Enzyme Link: ExplorEnz 1.14.11.17
PRIAM enzyme-specific profiles Link: PRIAM 1.14.11.17
IntEnz Enzyme Link: IntEnz 1.14.11.17
MEDLINE Enzyme Link: MEDLINE 1.14.11.17

EC number:1.14.11.17

MSA:

1.14.11.17;
Phylogenetic Tree:

1.14.11.17;
Uniprot:
M-CSA:
RHEA:15909 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + H(+) + succinate + sulfite
RULE(radius=1) [*:1]=[C;H0;+0:2](-[OH;+0:3])-[C;H0;+0:4](=[*:5])-[*:6].[*:7]=[S;H0;+0:8](-[*:9])(=[O;H0;+0:10])-[CH2;+0:11]-[*:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:12]-[CH;+0:11]=[O;H0;+0:14].[*:5]=[C;H0;+0:4](-[*:6])-[OH;+0:13].[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[*:7]=[S;H0;+0:8](-[*:9])-[OH;+0:10]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates.Elkins JM, Ryle MJ, Clifton IJ, Dunning Hotopp JC, Lloyd JS, Burzlaff NI, Baldwin JE, Hausinger RP, Roach PL2002 Apr 2311955067