EC number:1.14.11.32

Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
ID:1.14.11.32
Description:Codeine 3-O-demethylase.
Alternative Name: Codeine O-demethylase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.11.32
BRENDA Enzyme Link: BRENDA 1.14.11.32
KEGG Enzyme Link: KEGG1.14.11.32
BioCyc Enzyme Link: BioCyc 1.14.11.32
ExPASy Enzyme Link: ExPASy1.14.11.32
EC2PDB Enzyme Link: EC2PDB 1.14.11.32
ExplorEnz Enzyme Link: ExplorEnz 1.14.11.32
PRIAM enzyme-specific profiles Link: PRIAM 1.14.11.32
IntEnz Enzyme Link: IntEnz 1.14.11.32
MEDLINE Enzyme Link: MEDLINE 1.14.11.32

EC number:1.14.11.32

MSA:

1.14.11.32;
Phylogenetic Tree:

1.14.11.32;
Uniprot:
M-CSA:
RHEA:27413 2-oxoglutarate + codeine + O2 = CO2 + formaldehyde + morphine + succinate
RULE(radius=1) [*:1]:[c;H0;+0:2](:[*:3])-[O;H0;+0:4]-[CH3;+0:5].[*:6]=[C;H0;+0:7](-[OH;+0:8])-[C;H0;+0:9](=[*:10])-[*:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]:[c;H0;+0:2](:[*:3])-[OH;+0:12].[*:10]=[C;H0;+0:9](-[*:11])-[OH;+0:13].[*:6]=[C;H0;+0:7]=[O;H0;+0:8].[CH2;+0:5]=[O;H0;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.Hagel JM, Facchini PJ2010 Apr20228795