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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

ID:	1.14.11.36
Description:	Pentalenolactone F synthase.

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UniProtKB Enzyme Link:	UniProtKB 1.14.11.36
BRENDA Enzyme Link:	BRENDA 1.14.11.36
KEGG Enzyme Link:	KEGG1.14.11.36
BioCyc Enzyme Link:	BioCyc 1.14.11.36
ExPASy Enzyme Link:	ExPASy1.14.11.36
EC2PDB Enzyme Link:	EC2PDB 1.14.11.36
ExplorEnz Enzyme Link:	ExplorEnz 1.14.11.36
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.11.36
IntEnz Enzyme Link:	IntEnz 1.14.11.36
MEDLINE Enzyme Link:	MEDLINE 1.14.11.36

RHEA:34579	2 2-oxoglutarate + 2 O2 + pentalenolactone D = 2 CO2 + H2O + pentalenolactone F + 2 succinate
RULE(radius=1)	[:1]-[CH;+0:2](-[:3])-[CH3;+0:4].[:5]=[C;H0;+0:6](-[OH;+0:7])-[C;H0;+0:8](=[:9])-[:10].[:11]=[C;H0;+0:12](-[OH;+0:13])-[C;H0;+0:14](=[:15])-[:16].[O;H0;+0:17]=[O;H0;+0:18].[O;H0;+0:19]=[O;H0;+0:20]>>[:1]-[C;H0;+0:2]1(-[:3])-[CH2;+0:4]-[O;H0;+0:17]-1.[:9]=[C;H0;+0:8](-[:10])-[OH;+0:18].[:15]=[C;H0;+0:14](-[:16])-[OH;+0:19].[:5]=[C;H0;+0:6]=[O;H0;+0:7].[:11]=[C;H0;+0:12]=[O;H0;+0:13].[OH2;+0:20]
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Title	Authors	Date	PubMed ID
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.	Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE	2011 Mar 15	21250661