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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

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UniProtKB Enzyme Link:	UniProtKB 1.14.11.38
BRENDA Enzyme Link:	BRENDA 1.14.11.38
KEGG Enzyme Link:	KEGG1.14.11.38
BioCyc Enzyme Link:	BioCyc 1.14.11.38
ExPASy Enzyme Link:	ExPASy1.14.11.38
EC2PDB Enzyme Link:	EC2PDB 1.14.11.38
ExplorEnz Enzyme Link:	ExplorEnz 1.14.11.38
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.11.38
IntEnz Enzyme Link:	IntEnz 1.14.11.38
MEDLINE Enzyme Link:	MEDLINE 1.14.11.38

RHEA:35975	2-oxoglutarate + AH2 + fumitremorgin B + 2 O2 = A + CO2 + H2O + succinate + verruculogen
RULE(radius=1)	([:1]-[CH2;+0:2]-[:3].[:4]-[CH;+0:5]=[C;H0;+0:6](-[:7])-[:8]).[:9]=[C;H0;+0:10](-[OH;+0:11])-[C;H0;+0:12](=[:13])-[:14].[O;H0;+0:15]=[O;H0;+0:16].[O;H0;+0:17]=[O;H0;+0:18]>>[:1]-[CH;+0:2](-[:3])-[O;H0;+0:15]-[O;H0;+0:16]-[C;H0;+0:6](-[:7])(-[:8])-[CH2;+0:5]-[:4].[:13]=[C;H0;+0:12](-[:14])-[OH;+0:17].[:9]=[C;H0;+0:10]=[O;H0;+0:11].[OH2;+0:18]
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Title	Authors	Date	PubMed ID
Gene disruption and biochemical characterization of verruculogen synthase of Aspergillus fumigatus.	Kato N, Suzuki H, Takagi H, Uramoto M, Takahashi S, Osada H	2011 Mar 21	21404415
FtmOx1, a non-heme Fe(II) and alpha-ketoglutarate-dependent dioxygenase, catalyses the endoperoxide formation of verruculogen in Aspergillus fumigatus.	Steffan N, Grundmann A, Afiyatullov S, Ruan H, Li SM	2009 Oct 7	19763315