EC number:1.14.11.47

Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
ID:1.14.11.47
Description:[50S ribosomal protein L16]-arginine 3-hydroxylase.
Cath: 1.10.10.2510; 2.60.120.650;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.11.47
BRENDA Enzyme Link: BRENDA 1.14.11.47
KEGG Enzyme Link: KEGG1.14.11.47
BioCyc Enzyme Link: BioCyc 1.14.11.47
ExPASy Enzyme Link: ExPASy1.14.11.47
EC2PDB Enzyme Link: EC2PDB 1.14.11.47
ExplorEnz Enzyme Link: ExplorEnz 1.14.11.47
PRIAM enzyme-specific profiles Link: PRIAM 1.14.11.47
IntEnz Enzyme Link: IntEnz 1.14.11.47
MEDLINE Enzyme Link: MEDLINE 1.14.11.47

EC number:1.14.11.47

MSA:

1.14.11.47;
Phylogenetic Tree:

1.14.11.47;
Uniprot:
M-CSA:
RHEA:41556 2-oxoglutarate + L-arginyl-[ribosomal protein uL16] + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein uL16] + CO2 + succinate
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]=[C;H0;+0:5](-[OH;+0:6])-[C;H0;+0:7](=[*:8])-[*:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:10].[*:8]=[C;H0;+0:7](-[*:9])-[OH;+0:11].[*:4]=[C;H0;+0:5]=[O;H0;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.Ge W, Wolf A, Feng T, Ho CH, Sekirnik R, Zayer A, Granatino N, Cockman ME, Loenarz C, Loik ND, Hardy AP, Claridge TDW, Hamed RB, Chowdhury R, Gong L, Robinson CV, Trudgian DC, Jiang M, Mackeen MM, Mccullagh JS, Gordiyenko Y, Thalhammer A, Yamamoto A, Yang M, Liu-Yi P, Zhang Z, Schmidt-Zachmann M, Kessler BM, Ratcliffe PJ, Preston GM, Coleman ML, Schofield CJ2012 Dec23103944
Structure and functional analysis of YcfD, a novel 2-oxoglutarate/Fe²⁺-dependent oxygenase involved in translational regulation in Escherichia coli.van Staalduinen LM, Novakowski SK, Jia Z2014 May 124530688