Title | Authors | Date | PubMed ID |
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation. | Xu C, Liu K, Tempel W, Demetriades M, Aik W, Schofield CJ, Min J | 2014 Jun 20 | 24778178 |
Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition. | Feng C, Liu Y, Wang G, Deng Z, Zhang Q, Wu W, Tong Y, Cheng C, Chen Z | 2014 Apr 25 | 24616105 |
Structure of human RNA N⁶-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation. | Aik W, Scotti JS, Choi H, Gong L, Demetriades M, Schofield CJ, McDonough MA | 2014 Apr | 24489119 |
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. | Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C | 2013 Jan 10 | 23177736 |
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. | Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, He C | 2011 Oct 16 | 22002720 |
Crystal structure of the FTO protein reveals basis for its substrate specificity. | Han Z, Niu T, Chang J, Lei X, Zhao M, Wang Q, Cheng W, Wang J, Feng Y, Chai J | 2010 Apr 22 | 20376003 |
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. | Jia G, Yang CG, Yang S, Jian X, Yi C, Zhou Z, He C | 2008 Oct 15 | 18775698 |