Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.134
Description:Beta-amyrin 24-hydroxylase.
Alternative Name: Sophoradiol 24-hydroxylase.
CYP93E1.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.134
BRENDA Enzyme Link: BRENDA 1.14.14.134
KEGG Enzyme Link: KEGG1.14.14.134
BioCyc Enzyme Link: BioCyc 1.14.14.134
ExPASy Enzyme Link: ExPASy1.14.14.134
EC2PDB Enzyme Link: EC2PDB 1.14.14.134
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.134
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.134
IntEnz Enzyme Link: IntEnz 1.14.14.134
MEDLINE Enzyme Link: MEDLINE 1.14.14.134
MSA:

1.14.14.134;

Phylogenetic Tree:

1.14.14.134;

Uniprot:
M-CSA:
RHEA:30995 O2 + reduced [NADPH--hemoprotein reductase] + sophoradiol = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + soyasapogenol B
RULE(radius=1) [*:1]-[CH3;+0:2].[*:3]:[nH;+0:4]:[c;H0;+0:5]1:[c;H0;+0:6](:[*:7])-[NH;+0:8]-[*:9]:[*:10]-[N;H0;+0:11]-1-[*:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH2;+0:2]-[OH;+0:13].[*:3]:[n;H0;+0:4]:[c;H0;+0:5]1:[n;H0;+0:11](-[*:12]):[*:10]:[*:9]:[n;H0;+0:8]:[c;H0;+0:6]-1:[*:7].[OH2;+0:14]
Reaction
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References

TitleAuthorsDatePubMed ID
Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay.Shibuya M, Hoshino M, Katsube Y, Hayashi H, Kushiro T, Ebizuka Y2006 Mar16478469

RHEA:30991 beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 24-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[*:5]:[*:6]-[NH;+0:7]-[c;H0;+0:8](:[*:9]):[c;H0;+0:10]-1:[nH;+0:11]:[*:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH2;+0:2]-[OH;+0:13].[*:3]-[n;H0;+0:4]1:[*:5]:[*:6]:[n;H0;+0:7]:[c;H0;+0:8](:[*:9])-[c;H0;+0:10]:1:[n;H0;+0:11]:[*:12].[OH2;+0:14]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay.Shibuya M, Hoshino M, Katsube Y, Hayashi H, Kushiro T, Ebizuka Y2006 Mar16478469