EC number:1.14.14.158
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.158 |
|---|---|
| Description: | Carotene epsilon-hydroxylase. |
| Alternative Name: |
LUT1. CYP97C1. CYP97C. Carotene epsilon-monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.158 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.158 |
| KEGG Enzyme Link: | KEGG1.14.14.158 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.158 |
| ExPASy Enzyme Link: | ExPASy1.14.14.158 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.158 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.158 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.158 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.158 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.158 |
EC number:1.14.14.158
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:30399 | alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[OH2;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Arabidopsis carotenoid mutants demonstrate that lutein is not essential for photosynthesis in higher plants. | Pogson B, McDonald KA, Truong M, Britton G, DellaPenna D | 1996 Sep | 8837513 |
| The evolution and function of carotenoid hydroxylases in Arabidopsis. | Kim J, Smith JJ, Tian L, Dellapenna D | 2009 Mar | 19147649 |
| The Arabidopsis LUT1 locus encodes a member of the cytochrome p450 family that is required for carotenoid epsilon-ring hydroxylation activity. | Tian L, Musetti V, Kim J, Magallanes-Lundback M, DellaPenna D | 2004 Jan 6 | 14709673 |
| Molecular Cloning and Characterization of Carotenoid Pathway Genes and Carotenoid Content in Ixeris dentata var. albiflora. | Reddy CS, Lee SH, Yoon JS, Kim JK, Lee SW, Hur M, Koo SC, Meilan J, Lee WM, Jang JK, Hur Y, Park SU, Kim AYB | 2017 Aug 31 | 28858245 |
| Cloning and Functional Characterization of the Maize (Zea mays L.) Carotenoid Epsilon Hydroxylase Gene. | Chang S, Berman J, Sheng Y, Wang Y, Capell T, Shi L, Ni X, Sandmann G, Christou P, Zhu C | 2015 | 26030746 |
| Characterization of P450 carotenoid beta- and epsilon-hydroxylases of tomato and transcriptional regulation of xanthophyll biosynthesis in root, leaf, petal and fruit. | Stigliani AL, Giorio G, D'Ambrosio C | 2011 May | 21450689 |