EC number:1.14.14.28
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.28 |
|---|---|
| Description: | Long-chain alkane monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.28 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.28 |
| KEGG Enzyme Link: | KEGG1.14.14.28 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.28 |
| ExPASy Enzyme Link: | ExPASy1.14.14.28 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.28 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.28 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.28 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.28 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.28 |
EC number:1.14.14.28
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:49060 | a long-chain alkane + FMNH2 + O2 = a long chain fatty alcohol + FMN + H(+) + H2O |
| RULE(radius=1) | [*;H0;+0:1].[*:2]-[N;H0;+0:3]1-[*:4]:[*:5]-[NH;+0:6]-[c;H0;+0:7](:[*:8]):[c;H0;+0:9]-1:[nH;+0:10]:[*:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*;H0;+0:1]-[OH;+0:13].[*:2]-[n;H0;+0:3]1:[*:4]:[*:5]:[n;H0;+0:6]:[c;H0;+0:7](:[*:8])-[c;H0;+0:9]:1:[n;H0;+0:10]:[*:11].[OH2;+0:12] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Engineering of LadA for enhanced hexadecane oxidation using random- and site-directed mutagenesis. | Dong Y, Yan J, Du H, Chen M, Ma T, Feng L | 2012 May | 22526792 |
| Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase. | Li L, Liu X, Yang W, Xu F, Wang W, Feng L, Bartlam M, Wang L, Rao Z | 2008 Feb 15 | 18164311 |
| Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir. | Feng L, Wang W, Cheng J, Ren Y, Zhao G, Gao C, Tang Y, Liu X, Han W, Peng X, Liu R, Wang L | 2007 Mar 27 | 17372208 |