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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

ID:

1.14.14.98

Description:

Protopine 6-monooxygenase.

Alternative Name:

Protopine 6-hydroxylase.
CYP82N2.

Prosite:

PDOC00081;

PDB:

PDB	Scop

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UniProtKB Enzyme Link:	UniProtKB 1.14.14.98
BRENDA Enzyme Link:	BRENDA 1.14.14.98
KEGG Enzyme Link:	KEGG1.14.14.98
BioCyc Enzyme Link:	BioCyc 1.14.14.98
ExPASy Enzyme Link:	ExPASy1.14.14.98
EC2PDB Enzyme Link:	EC2PDB 1.14.14.98
ExplorEnz Enzyme Link:	ExplorEnz 1.14.14.98
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.14.98
IntEnz Enzyme Link:	IntEnz 1.14.14.98
MEDLINE Enzyme Link:	MEDLINE 1.14.14.98

RHEA:22644	O2 + protopine + reduced [NADPH--hemoprotein reductase] = 6-hydroxyprotopine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1)	[:1]-[CH2;+0:2]-[:3].[:4]-[N;H0;+0:5]1-[CH;+0:6]=[C;H0;+0:7](-[:8])-[CH2;+0:9]-[CH;+0:10]=[CH;+0:11]-1.[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[:1]-[CH;+0:2](-[:3])-[OH;+0:13].[:4]-[n+;H0:5]1:[cH;+0:6]:[c;H0;+0:7](-[:8]):[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:1.[OH2;+0:14]
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Core-to-Core	More

Title	Authors	Date	PubMed ID
Molecular cloning and characterization of a cytochrome P450 in sanguinarine biosynthesis from Eschscholzia californica cells.	Takemura T, Ikezawa N, Iwasa K, Sato F	2013 Jul	22421633