EC number:1.14.19.25
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.25 |
|---|---|
| Description: | Acyl-lipid omega-3 desaturase (cytochrome b5). |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.19.25 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.25 |
| KEGG Enzyme Link: | KEGG1.14.19.25 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.25 |
| ExPASy Enzyme Link: | ExPASy1.14.19.25 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.25 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.25 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.25 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.25 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.25 |
EC number:1.14.19.25
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46404 | 2 [Fe(II)-cytochrome b5] + a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 = (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 [Fe(III)-cytochrome b5] + 2 H2O |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[Fe+2;H0:5].[Fe+2;H0:6].[H+;H0:7].[H+;H0:8].[O;H0;+0:9]=[O;H0;+0:10]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[Fe+3;H0:5].[Fe+3;H0:6].[OH2;+0:9].[OH2;+0:10] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mutants of Arabidopsis deficient in the synthesis of alpha-linolenate. Biochemical and genetic characterization of the endoplasmic reticulum linoleoyl desaturase. | Browse J, McConn M, James D Jr, Miquel M | 1993 Aug 5 | 8102138 |
| A novel fungal omega3-desaturase with wide substrate specificity from arachidonic acid-producing Mortierella alpina 1S-4. | Sakuradani E, Abe T, Iguchi K, Shimizu S | 2005 Mar | 15538555 |
| Map-based cloning of a gene controlling omega-3 fatty acid desaturation in Arabidopsis. | Arondel V, Lemieux B, Hwang I, Gibson S, Goodman HM, Somerville CR | 1992 Nov 20 | 1455229 |