EC number:1.14.19.33

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
ID:1.14.19.33
Description:Delta(12) acyl-lipid conjugase (11E,13E-forming).
Alternative Name: Fatty acid Delta(12)-conjugase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.19.33
BRENDA Enzyme Link: BRENDA 1.14.19.33
KEGG Enzyme Link: KEGG1.14.19.33
BioCyc Enzyme Link: BioCyc 1.14.19.33
ExPASy Enzyme Link: ExPASy1.14.19.33
EC2PDB Enzyme Link: EC2PDB 1.14.19.33
ExplorEnz Enzyme Link: ExplorEnz 1.14.19.33
PRIAM enzyme-specific profiles Link: PRIAM 1.14.19.33
IntEnz Enzyme Link: IntEnz 1.14.19.33
MEDLINE Enzyme Link: MEDLINE 1.14.19.33

EC number:1.14.19.33

MSA:

1.14.19.33;
Phylogenetic Tree:

1.14.19.33;
Uniprot:
M-CSA:
RHEA:46372 (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 H2O
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[*:6].[Fe+2;H0:7].[Fe+2;H0:8].[H+;H0:9].[H+;H0:10].[O;H0;+0:11]=[O;H0;+0:12]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[CH;+0:4]=[CH;+0:5]-[*:6].[Fe+3;H0:7].[Fe+3;H0:8].[OH2;+0:11].[OH2;+0:12]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthetic origin of conjugated double bonds: production of fatty acid components of high-value drying oils in transgenic soybean embryos.Cahoon EB, Carlson TJ, Ripp KG, Schweiger BJ, Cook GA, Hall SE, Kinney AJ1999 Oct 2610536026
Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity.Dyer JM, Chapital DC, Kuan JC, Mullen RT, Turner C, McKeon TA, Pepperman AB2002 Dec12481086
RHEA:46368 2 [Fe(II)-cytochrome b5] + a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid + 2 H2O
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[*:6].[Fe+2;H0:7].[Fe+2;H0:8].[H+;H0:9].[H+;H0:10].[O;H0;+0:11]=[O;H0;+0:12]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[CH;+0:4]=[CH;+0:5]-[*:6].[Fe+3;H0:7].[Fe+3;H0:8].[OH2;+0:11].[OH2;+0:12]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthetic origin of conjugated double bonds: production of fatty acid components of high-value drying oils in transgenic soybean embryos.Cahoon EB, Carlson TJ, Ripp KG, Schweiger BJ, Cook GA, Hall SE, Kinney AJ1999 Oct 2610536026
Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity.Dyer JM, Chapital DC, Kuan JC, Mullen RT, Turner C, McKeon TA, Pepperman AB2002 Dec12481086