Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
ID:1.14.19.34
Description:Acyl-lipid (9+3)-(E)-desaturase.
Alternative Name: Acyl-lipid 12-(E)-desaturase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.19.34
BRENDA Enzyme Link: BRENDA 1.14.19.34
KEGG Enzyme Link: KEGG1.14.19.34
BioCyc Enzyme Link: BioCyc 1.14.19.34
ExPASy Enzyme Link: ExPASy1.14.19.34
EC2PDB Enzyme Link: EC2PDB 1.14.19.34
ExplorEnz Enzyme Link: ExplorEnz 1.14.19.34
PRIAM enzyme-specific profiles Link: PRIAM 1.14.19.34
IntEnz Enzyme Link: IntEnz 1.14.19.34
MEDLINE Enzyme Link: MEDLINE 1.14.19.34
MSA:

1.14.19.34;

Phylogenetic Tree:

1.14.19.34;

Uniprot:
M-CSA:
RHEA:46240 2 [Fe(II)-cytochrome b5] + a (9Z)-hexadecenoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z,12E)-hexadecadienoyl-containing glycerolipid + 2 H2O
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[Fe+2;H0:5].[Fe+2;H0:6].[H+;H0:7].[H+;H0:8].[O;H0;+0:9]=[O;H0;+0:10]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[Fe+3;H0:5].[Fe+3;H0:6].[OH2;+0:9].[OH2;+0:10]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Dimorphecolic acid is synthesized by the coordinate activities of two divergent Delta12-oleic acid desaturases.Cahoon EB, Kinney AJ2004 Mar 2614718523
Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity.Dyer JM, Chapital DC, Kuan JC, Mullen RT, Turner C, McKeon TA, Pepperman AB2002 Dec12481086

RHEA:38047 2 [Fe(II)-cytochrome b5] + a (9Z)-octadecenoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z,12E)-octadecadienoyl-containing glycerolipid + 2 H2O
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[Fe+2;H0:5].[Fe+2;H0:6].[H+;H0:7].[H+;H0:8].[O;H0;+0:9]=[O;H0;+0:10]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[Fe+3;H0:5].[Fe+3;H0:6].[OH2;+0:9].[OH2;+0:10]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Dimorphecolic acid is synthesized by the coordinate activities of two divergent Delta12-oleic acid desaturases.Cahoon EB, Kinney AJ2004 Mar 2614718523
Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity.Dyer JM, Chapital DC, Kuan JC, Mullen RT, Turner C, McKeon TA, Pepperman AB2002 Dec12481086