EC number:1.14.19.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.5 |
|---|---|
| Description: | Acyl-CoA 11-(Z)-desaturase. |
| Alternative Name: |
Z/E11-desaturase. Fatty acid Delta(11)-desaturase. Delta(11)-palmitoyl-CoA desaturase. Delta(11)-fatty-acid desaturase. Delta(11) desaturase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.19.5 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.5 |
| KEGG Enzyme Link: | KEGG1.14.19.5 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.5 |
| ExPASy Enzyme Link: | ExPASy1.14.19.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.5 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.5 |
EC number:1.14.19.5
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:25852 | 2 [Fe(II)-cytochrome b5] + an 11,12-saturated fatty acyl-CoA + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + an (11Z)-Delta(11)-fatty acyl-CoA + 2 H2O |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[Fe+2;H0:5].[Fe+2;H0:6].[H+;H0:7].[H+;H0:8].[O;H0;+0:9]=[O;H0;+0:10]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[Fe+3;H0:5].[Fe+3;H0:6].[OH2;+0:9].[OH2;+0:10] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cloning and functional expression of a cDNA encoding a pheromone gland-specific acyl-CoA Delta11-desaturase of the cabbage looper moth, Trichoplusia ni. | Knipple DC, Rosenfield CL, Miller SJ, Liu W, Tang J, Ma PW, Roelofs WL | 1998 Dec 22 | 9860961 |
| Expression and evolution of delta9 and delta11 desaturase genes in the moth Spodoptera littoralis. | Rodríguez S, Hao G, Liu W, Piña B, Rooney AP, Camps F, Roelofs WL, Fabriàs G | 2004 Dec | 15544945 |
| Characterization of Z/E11- and Z9-desaturases from the obliquebanded leafroller moth, Choristoneura rosaceana. | Hao G, O'Connor M, Liu W, Roelofs WL | 2002 | 15455060 |
| Involvement of a bifunctional fatty-acyl desaturase in the biosynthesis of the silkmoth, Bombyx mori, sex pheromone. | Moto K, Suzuki MG, Hull JJ, Kurata R, Takahashi S, Yamamoto M, Okano K, Imai K, Ando T, Matsumoto S | 2004 Jun 8 | 15173596 |
| Identification of a fatty acid Delta11-desaturase from the microalga Thalassiosira pseudonana. | Tonon T, Harvey D, Qing R, Li Y, Larson TR, Graham IA | 2004 Apr 9 | 15063718 |