EC number:1.14.20.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated |
| ID: | 1.14.20.5 | ||
|---|---|---|---|
| Description: | Flavone synthase I. | ||
| Alternative Name: |
FNS I. | ||
| Prosite: | PDOC51471; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.20.5 |
| BRENDA Enzyme Link: | BRENDA 1.14.20.5 |
| KEGG Enzyme Link: | KEGG1.14.20.5 |
| BioCyc Enzyme Link: | BioCyc 1.14.20.5 |
| ExPASy Enzyme Link: | ExPASy1.14.20.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.20.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.20.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.20.5 |
| IntEnz Enzyme Link: | IntEnz 1.14.20.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.20.5 |
EC number:1.14.20.5
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:32755 | (S)-naringenin + 2-oxoglutarate + O2 = apigenin + CO2 + H(+) + H2O + succinate |
| RULE(radius=1) | [*:1]:[c;H0;+0:2](:[*:3])-[CH;+0:4]1-[CH2;+0:5]-[C;H0;+0:6](=[*:7])-[*:8]:[*:9]-[O;H0;+0:10]-1.[*:11]=[C;H0;+0:12](-[OH;+0:13])-[C;H0;+0:14](=[*:15])-[*:16].[O;H0;+0:17]=[O;H0;+0:18]>>[*:1]:[c;H0;+0:2](:[*:3])-[c;H0;+0:4]1:[cH;+0:5]:[c;H0;+0:6](=[*:7]):[*:8]:[*:9]:[o;H0;+0:10]:1.[*:15]=[C;H0;+0:14](-[*:16])-[OH;+0:17].[*:11]=[C;H0;+0:12]=[O;H0;+0:13].[OH2;+0:18] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cloning of parsley flavone synthase I. | Martens S, Forkmann G, Matern U, Lukacin R | 2001 Sep | 11524111 |
| RHEA:10448 | 2-oxoglutarate + a flavanone + O2 = a flavone + CO2 + H2O + succinate |
| RULE(radius=1) | [*:1]:[c;H0;+0:2](:[*:3])-[CH;+0:4]1-[CH2;+0:5]-[C;H0;+0:6](=[*:7])-[*:8]:[*:9]-[O;H0;+0:10]-1.[*:11]=[C;H0;+0:12](-[OH;+0:13])-[C;H0;+0:14](=[*:15])-[*:16].[O;H0;+0:17]=[O;H0;+0:18]>>[*:1]:[c;H0;+0:2](:[*:3])-[c;H0;+0:4]1:[cH;+0:5]:[c;H0;+0:6](=[*:7]):[*:8]:[*:9]:[o;H0;+0:10]:1.[*:15]=[C;H0;+0:14](-[*:16])-[OH;+0:17].[*:11]=[C;H0;+0:12]=[O;H0;+0:13].[OH2;+0:18] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley. | Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R | 2003 Jun 5 | 12782296 |
| Cloning of parsley flavone synthase I. | Martens S, Forkmann G, Matern U, Lukacin R | 2001 Sep | 11524111 |
| Purification and antigenicity of flavone synthase I from irradiated parsley cells. | Lukacin R, Matern U, Junghanns KT, Heskamp ML, Britsch L, Forkmann G, Martens S | 2001 Sep 1 | 11516175 |