EC number:1.14.99.4
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.99 Miscellaneous |
| ID: | 1.14.99.4 |
|---|---|
| Description: | Progesterone monooxygenase. |
| Alternative Name: |
Progesterone hydroxylase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.99.4 |
| BRENDA Enzyme Link: | BRENDA 1.14.99.4 |
| KEGG Enzyme Link: | KEGG1.14.99.4 |
| BioCyc Enzyme Link: | BioCyc 1.14.99.4 |
| ExPASy Enzyme Link: | ExPASy1.14.99.4 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.99.4 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.99.4 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.99.4 |
| IntEnz Enzyme Link: | IntEnz 1.14.99.4 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.99.4 |
EC number:1.14.99.4
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:11984 | AH2 + O2 + progesterone = A + H2O + testosterone acetate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[C;H0;+0:4](=[*:5])-[*:6].[O;H0;+0:7]=[O;H0;+0:8]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:7]-[C;H0;+0:4](=[*:5])-[*:6].[OH2;+0:8] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mechanisms of steroid oxidation by microorganisms. XI. Enzymatic cleavage of the pregnane side chain. | Rahm MA, Sih CJ | 1966 Aug 10 | 5950688 |