EC number:1.14.99.50
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.99 Miscellaneous |
| ID: | 1.14.99.50 |
|---|---|
| Description: | Gamma-glutamyl hercynylcysteine S-oxide synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.99.50 |
| BRENDA Enzyme Link: | BRENDA 1.14.99.50 |
| KEGG Enzyme Link: | KEGG1.14.99.50 |
| BioCyc Enzyme Link: | BioCyc 1.14.99.50 |
| ExPASy Enzyme Link: | ExPASy1.14.99.50 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.99.50 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.99.50 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.99.50 |
| IntEnz Enzyme Link: | IntEnz 1.14.99.50 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.99.50 |
EC number:1.14.99.50
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:42672 | hercynine + L-gamma-glutamyl-L-cysteine + O2 = H2O + L-gamma-glutamyl-hercynylcysteine S-oxide |
| RULE(radius=1) | [*:1]-[SH;+0:2].[*:3]:[cH;+0:4]:[*:5].[O;H0;+0:6]=[O;H0;+0:7]>>[*:1]-[S;H0;+0:2](=[O;H0;+0:6])-[c;H0;+0:4](:[*:3]):[*:5].[OH2;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| In vitro reconstitution of Mycobacterial ergothioneine biosynthesis. | Seebeck FP | 2010 May 19 | 20420449 |
| Structure of the sulfoxide synthase EgtB from the ergothioneine biosynthetic pathway. | Goncharenko KV, Vit A, Blankenfeldt W, Seebeck FP | 2015 Feb 23 | 25597398 |
| Genetic and metabolomic dissection of the ergothioneine and selenoneine biosynthetic pathway in the fission yeast, S. pombe, and construction of an overproduction system. | Pluskal T, Ueno M, Yanagida M | 2014 | 24828577 |