Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.3 With oxygen as acceptor
ID:1.2.3.15
Description:(Methyl)glyoxal oxidase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.3.15
BRENDA Enzyme Link: BRENDA 1.2.3.15
KEGG Enzyme Link: KEGG1.2.3.15
BioCyc Enzyme Link: BioCyc 1.2.3.15
ExPASy Enzyme Link: ExPASy1.2.3.15
EC2PDB Enzyme Link: EC2PDB 1.2.3.15
ExplorEnz Enzyme Link: ExplorEnz 1.2.3.15
PRIAM enzyme-specific profiles Link: PRIAM 1.2.3.15
IntEnz Enzyme Link: IntEnz 1.2.3.15
MEDLINE Enzyme Link: MEDLINE 1.2.3.15
MSA:

1.2.3.15;

Phylogenetic Tree:

1.2.3.15;

Uniprot:
M-CSA:
RHEA:49636 H2O + methylglyoxal + O2 = H(+) + H2O2 + pyruvate
RULE(radius=1) [*:1]=[CH;+0:2]-[*:3].[O;H0;+0:4]=[O;H0;+0:5].[OH2;+0:6]>>[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:6].[OH;+0:4]-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Glyoxal oxidase from Phanerochaete chrysosporium is a new radical-copper oxidase.Whittaker MM, Kersten PJ, Nakamura N, Sanders-Loehr J, Schweizer ES, Whittaker JW1996 Jan 128557673
Cloning and characterization of cDNA encoding glyoxal oxidase, a H2O2-producing enzyme from the lignin-degrading basidiomycete Phanerochaete chrysosporium.Kersten PJ, Cullen D1993 Aug 18346264
Phanerochaete chrysosporium glyoxal oxidase is encoded by two allelic variants: structure, genomic organization, and heterologous expression of glx1 and glx2.Kersten PJ, Witek C, vanden Wymelenberg A, Cullen D1995 Nov7592374
Involvement of a new enzyme, glyoxal oxidase, in extracellular H2O2 production by Phanerochaete chrysosporium.Kersten PJ, Kirk TK1987 May3553159

RHEA:33439 glyoxal + H2O + O2 = glyoxylate + H(+) + H2O2
RULE(radius=1) [*:1]-[CH;+0:2]=[*:3].[O;H0;+0:4]=[O;H0;+0:5].[OH2;+0:6]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:6].[OH;+0:4]-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Glyoxal oxidase from Phanerochaete chrysosporium is a new radical-copper oxidase.Whittaker MM, Kersten PJ, Nakamura N, Sanders-Loehr J, Schweizer ES, Whittaker JW1996 Jan 128557673
Cloning and characterization of cDNA encoding glyoxal oxidase, a H2O2-producing enzyme from the lignin-degrading basidiomycete Phanerochaete chrysosporium.Kersten PJ, Cullen D1993 Aug 18346264
Phanerochaete chrysosporium glyoxal oxidase is encoded by two allelic variants: structure, genomic organization, and heterologous expression of glx1 and glx2.Kersten PJ, Witek C, vanden Wymelenberg A, Cullen D1995 Nov7592374
Involvement of a new enzyme, glyoxal oxidase, in extracellular H2O2 production by Phanerochaete chrysosporium.Kersten PJ, Kirk TK1987 May3553159