Enzyme

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EC Tree
     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.99 With unknown physiological acceptors
ID:1.2.99.6
Description:Carboxylate reductase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.99.6
BRENDA Enzyme Link: BRENDA 1.2.99.6
KEGG Enzyme Link: KEGG1.2.99.6
BioCyc Enzyme Link: BioCyc 1.2.99.6
ExPASy Enzyme Link: ExPASy1.2.99.6
EC2PDB Enzyme Link: EC2PDB 1.2.99.6
ExplorEnz Enzyme Link: ExplorEnz 1.2.99.6
PRIAM enzyme-specific profiles Link: PRIAM 1.2.99.6
IntEnz Enzyme Link: IntEnz 1.2.99.6
MEDLINE Enzyme Link: MEDLINE 1.2.99.6
MSA:

1.2.99.6;

Phylogenetic Tree:

1.2.99.6;

Uniprot:
M-CSA:
RHEA:56856 A + an aldehyde + H2O = a carboxylate + AH2 + H(+)
RULE(radius=1) [*:1]-[CH;+0:2]=[*:3].[OH2;+0:4]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of an aldehyde oxidase from Pseudomonas sp. KY 4690.Uchida H, Kondo D, Yamashita A, Nagaosa Y, Sakurai T, Fujii Y, Fujishiro K, Aisaka K, Uwajima T2003 Dec 514659539
Carboxylic acid reductase: a new tungsten enzyme catalyses the reduction of non-activated carboxylic acids to aldehydes.White H, Strobl G, Feicht R, Simon H1989 Sep 12550230
Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas.Romão MJ, Archer M, Moura I, Moura JJ, LeGall J, Engh R, Schneider M, Hof P, Huber R1995 Nov 177502041
Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB 13491 EPR assignment of the proximal [2Fe-2S] cluster to the Mo site.Andrade SL, Brondino CD, Feio MJ, Moura I, Moura JJ2000 Apr10727945
Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774.Duarte RO, Archer M, Dias JM, Bursakov S, Huber R, Moura I, Romão MJ, Moura JJ2000 Feb 2410679276