Enzyme

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EC Tree
     1. Oxidoreductases
        1.21 Catalysing the reaction X-H + Y-H = X-Y
            1.21.3 With oxygen as acceptor
ID:1.21.3.8
Description:Cannabidiolic acid synthase.
Alternative Name: CBDA synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.21.3.8
BRENDA Enzyme Link: BRENDA 1.21.3.8
KEGG Enzyme Link: KEGG1.21.3.8
BioCyc Enzyme Link: BioCyc 1.21.3.8
ExPASy Enzyme Link: ExPASy1.21.3.8
EC2PDB Enzyme Link: EC2PDB 1.21.3.8
ExplorEnz Enzyme Link: ExplorEnz 1.21.3.8
PRIAM enzyme-specific profiles Link: PRIAM 1.21.3.8
IntEnz Enzyme Link: IntEnz 1.21.3.8
MEDLINE Enzyme Link: MEDLINE 1.21.3.8
MSA:

1.21.3.8;

Phylogenetic Tree:

1.21.3.8;

Uniprot:
M-CSA:
RHEA:34411 cannabigerolate + O2 = cannabidiolate + H2O2
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH3;+0:8]).[O;H0;+0:9]=[O;H0;+0:10]>>[*:1]-[CH;+0:2](-[*:3])-[CH;+0:5](-[*:4])-[C;H0;+0:6](-[*:7])=[CH2;+0:8].[OH;+0:9]-[OH;+0:10]
Reaction
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References

TitleAuthorsDatePubMed ID
Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L.. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid.Taura F, Morimoto S, Shoyama Y1996 Jul 198663284
Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa.Taura F, Sirikantaramas S, Shoyama Y, Yoshikai K, Shoyama Y, Morimoto S2007 Jun 2617544411