EC number:1.3.1.85
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.85 |
|---|---|
| Description: | Crotonyl-CoA carboxylase/reductase. |
| Alternative Name: |
Crotonyl-CoA reductase (carboxylating). CCR. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.85 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.85 |
| KEGG Enzyme Link: | KEGG1.3.1.85 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.85 |
| ExPASy Enzyme Link: | ExPASy1.3.1.85 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.85 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.85 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.85 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.85 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.85 |
| RHEA:28082 | (2S)-ethylmalonyl-CoA + NADP(+) = (2E)-butenoyl-CoA + CO2 + NADPH |
| RULE(radius=1) | [*:1]-[c;H0;+0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[n+;H0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[C;H0;+0:10](-[OH;+0:11])-[CH;+0:12](-[*:13])-[CH2;+0:14]-[*:15]>>[*:1]-[C;H0;+0:2]1=[CH;+0:8]-[N;H0;+0:6](-[*:7])-[CH;+0:5]=[CH;+0:4]-[CH2;+0:3]-1.[*:15]-[CH;+0:14]=[CH;+0:12]-[*:13].[*:9]=[C;H0;+0:10]=[O;H0;+0:11] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase. | Erb TJ, Brecht V, Fuchs G, Müller M, Alber BE | 2009 Jun 2 | 19458256 |