EC Tree |
1. Oxidoreductases |
1.3 Acting on the CH-CH group of donors |
1.3.3 With oxygen as acceptor |
ID: | 1.3.3.15 |
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Description: | Coproporphyrinogen III oxidase (coproporphyrin-forming). |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.3.3.15 |
BRENDA Enzyme Link: | BRENDA 1.3.3.15 |
KEGG Enzyme Link: | KEGG1.3.3.15 |
BioCyc Enzyme Link: | BioCyc 1.3.3.15 |
ExPASy Enzyme Link: | ExPASy1.3.3.15 |
EC2PDB Enzyme Link: | EC2PDB 1.3.3.15 |
ExplorEnz Enzyme Link: | ExplorEnz 1.3.3.15 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.3.3.15 |
IntEnz Enzyme Link: | IntEnz 1.3.3.15 |
MEDLINE Enzyme Link: | MEDLINE 1.3.3.15 |
RHEA:43436 | coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2 |
RULE(radius=1) | ([*:1]-[CH2;+0:2]-[*:3]:[nH;+0:4]:[*:5]-[CH2;+0:6]-[*:7].[*:8]-[CH2;+0:9]-[*:10]:[nH;+0:11]:[*:12]-[CH2;+0:13]-[*:14]).[O;H0;+0:15]=[O;H0;+0:16].[O;H0;+0:17]=[O;H0;+0:18].[O;H0;+0:19]=[O;H0;+0:20]>>([*:1]:[cH;+0:2]:[*:3]:[n;H0;+0:4]:[*:5]:[cH;+0:6]:[*:7].[*:8]:[cH;+0:9]:[*:10]:[n;H0;+0:11]:[*:12]:[cH;+0:13]:[*:14]).[OH;+0:15]-[OH;+0:16].[OH;+0:17]-[OH;+0:18].[OH;+0:19]-[OH;+0:20] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Purification of and kinetic studies on a cloned protoporphyrinogen oxidase from the aerobic bacterium Bacillus subtilis. | Corrigall AV, Siziba KB, Maneli MH, Shephard EG, Ziman M, Dailey TA, Dailey HA, Kirsch RE, Meissner PN | 1998 Oct 15 | 9784236 |
Bacillus subtilis HemY is a peripheral membrane protein essential for protoheme IX synthesis which can oxidize coproporphyrinogen III and protoporphyrinogen IX. | Hansson M, Hederstedt L | 1994 Oct | 7928957 |
Noncanonical coproporphyrin-dependent bacterial heme biosynthesis pathway that does not use protoporphyrin. | Dailey HA, Gerdes S, Dailey TA, Burch JS, Phillips JD | 2015 Feb 17 | 25646457 |
Structural insight into unique properties of protoporphyrinogen oxidase from Bacillus subtilis. | Qin X, Sun L, Wen X, Yang X, Tan Y, Jin H, Cao Q, Zhou W, Xi Z, Shen Y | 2010 Apr | 19944166 |