EC number:1.3.3.3

Enzyme

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     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.3 With oxygen as acceptor
ID:1.3.3.3
Description:Coproporphyrinogen oxidase.
Alternative Name: Coproporphyrinogenase.
Coproporphyrinogen-III oxidase.
Coprogen oxidase.
Prosite: PDOC00783;
PDB:
PDBScop
1TLB 8027902; 8040281; 8027902; 8040281; 8027902; 8040281; 8027902; 8040281; 8027902; 8040281; 8027902; 8040281;
1TXN 8027902; 8040281; 8027902; 8040281;
1TKL 8027902; 8040281; 8027902; 8040281;
3DWS 8024000; 8036379; 8024000; 8036379;
3DWR 8024000; 8036379; 8024000; 8036379;
 » show all
Cath: 1.10.10.920; 3.80.30.20; 3.40.1500.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.3.3
BRENDA Enzyme Link: BRENDA 1.3.3.3
KEGG Enzyme Link: KEGG1.3.3.3
BioCyc Enzyme Link: BioCyc 1.3.3.3
ExPASy Enzyme Link: ExPASy1.3.3.3
EC2PDB Enzyme Link: EC2PDB 1.3.3.3
ExplorEnz Enzyme Link: ExplorEnz 1.3.3.3
PRIAM enzyme-specific profiles Link: PRIAM 1.3.3.3
IntEnz Enzyme Link: IntEnz 1.3.3.3
MEDLINE Enzyme Link: MEDLINE 1.3.3.3

EC number:1.3.3.3

MSA:

1.3.3.3;
Phylogenetic Tree:

1.3.3.3;
Uniprot:
M-CSA:
RHEA:18257 coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX
RULE(radius=1) ([*:1]-[CH2;+0:2]-[CH2;+0:3]-[C;H0;+0:4](=[*:5])-[OH;+0:6].[*:7]=[C;H0;+0:8](-[OH;+0:9])-[CH2;+0:10]-[CH2;+0:11]-[*:12]).[H+;H0:13].[H+;H0:14].[O;H0;+0:15]=[O;H0;+0:16]>>([*:1]-[CH;+0:2]=[CH2;+0:3].[*:12]-[CH;+0:11]=[CH2;+0:10]).[*:7]=[C;H0;+0:8]=[O;H0;+0:9].[*:5]=[C;H0;+0:4]=[O;H0;+0:6].[OH2;+0:15].[OH2;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Human coproporphyrinogen oxidase is not a metalloprotein.Medlock AE, Dailey HA1996 Dec 208955072
Coproporphyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid differentiation.Kohno H, Furukawa T, Yoshinaga T, Tokunaga R, Taketani S1993 Oct 58407975
Purification and properties of coproporphyrinogenase.del Batlle AM, Benson A, Rimington C1965 Dec5881662