EC number:1.3.4.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.4 With a disulfide as acceptor |
| ID: | 1.3.4.1 |
|---|---|
| Description: | Fumarate reductase (CoM/CoB). |
| Alternative Name: |
Thiol:fumarate reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.4.1 |
| BRENDA Enzyme Link: | BRENDA 1.3.4.1 |
| KEGG Enzyme Link: | KEGG1.3.4.1 |
| BioCyc Enzyme Link: | BioCyc 1.3.4.1 |
| ExPASy Enzyme Link: | ExPASy1.3.4.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.4.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.4.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.4.1 |
| IntEnz Enzyme Link: | IntEnz 1.3.4.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.4.1 |
| RHEA:40235 | coenzyme B + coenzyme M + fumarate = coenzyme M-coenzyme B heterodisulfide + succinate |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:5]-[SH;+0:6].[*:7]-[SH;+0:8]>>[*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[S;H0;+0:6]-[S;H0;+0:8]-[*:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Thiol:fumarate reductase (Tfr) from Methanobacterium thermoautotrophicum--identification of the catalytic sites for fumarate reduction and thiol oxidation. | Heim S, Künkel A, Thauer RK, Hedderich R | 1998 Apr 1 | 9578488 |
| Purification and characterization of an anabolic fumarate reductase from Methanobacterium thermoautotrophicum. | Khandekar SS, Eirich LD | 1989 Apr | 2499256 |