EC number:1.3.98.3
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.98 With other, known, physiological acceptors |
| ID: | 1.3.98.3 |
|---|---|
| Description: | Coproporphyrinogen dehydrogenase. |
| Alternative Name: |
Oxygen-independent coproporphyrinogen-III oxidase. Coproporphyrinogen III oxidase. |
| Cath: | 1.10.10.920; 3.80.30.20; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.98.3 |
| BRENDA Enzyme Link: | BRENDA 1.3.98.3 |
| KEGG Enzyme Link: | KEGG1.3.98.3 |
| BioCyc Enzyme Link: | BioCyc 1.3.98.3 |
| ExPASy Enzyme Link: | ExPASy1.3.98.3 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.98.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.98.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.98.3 |
| IntEnz Enzyme Link: | IntEnz 1.3.98.3 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.98.3 |
| RHEA:15425 | coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX |
| RULE(radius=1) | ([*:1]-[CH2;+0:2]-[CH2;+0:3]-[C;H0;+0:4](=[*:5])-[OH;+0:6].[*:7]=[C;H0;+0:8](-[OH;+0:9])-[CH2;+0:10]-[CH2;+0:11]-[*:12]).[*:13]-[S+;H0:14](-[*:15])-[CH2;+0:16]-[*:17]>>[*:17]-[CH3;+0:16].([*:1]-[CH;+0:2]=[CH2;+0:3].[*:12]-[CH;+0:11]=[CH2;+0:10]).[*:13]-[S;H0;+0:14]-[*:15].[*:7]=[C;H0;+0:8]=[O;H0;+0:9].[*:5]=[C;H0;+0:4]=[O;H0;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Functional differentiation of two analogous coproporphyrinogen III oxidases for heme and chlorophyll biosynthesis pathways in the cyanobacterium Synechocystis sp. PCC 6803. | Goto T, Aoki R, Minamizaki K, Fujita Y | 2010 Apr | 20194361 |
| Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes. | Layer G, Moser J, Heinz DW, Jahn D, Schubert WD | 2003 Dec 1 | 14633981 |
| Oxygen-independent coproporphyrinogen-III oxidase HemN from Escherichia coli. | Layer G, Verfürth K, Mahlitz E, Jahn D | 2002 Sep 13 | 12114526 |