Enzyme

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     1. Oxidoreductases
        1.4 Acting on the CH-NH2 group of donors
            1.4.3 With oxygen as acceptor
ID:1.4.3.19
Description:Glycine oxidase.
Cath: 3.30.9.10; 3.50.50.60;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.4.3.19
BRENDA Enzyme Link: BRENDA 1.4.3.19
KEGG Enzyme Link: KEGG1.4.3.19
BioCyc Enzyme Link: BioCyc 1.4.3.19
ExPASy Enzyme Link: ExPASy1.4.3.19
EC2PDB Enzyme Link: EC2PDB 1.4.3.19
ExplorEnz Enzyme Link: ExplorEnz 1.4.3.19
PRIAM enzyme-specific profiles Link: PRIAM 1.4.3.19
IntEnz Enzyme Link: IntEnz 1.4.3.19
MEDLINE Enzyme Link: MEDLINE 1.4.3.19
MSA:

1.4.3.19;

Phylogenetic Tree:

1.4.3.19;

Uniprot:
M-CSA:
RHEA:11532 glycine + H2O + O2 = glyoxylate + H2O2 + NH4(+)
RULE(radius=1) [*:1]-[CH2;+0:2]-[NH2;+0:3].[O;H0;+0:4]=[O;H0;+0:5].[OH2;+0:6]>>[*:1]-[CH;+0:2]=[O;H0;+0:6].[NH3;+0:3].[OH;+0:4]-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of a novel glycine oxidase from Bacillus subtilis.Nishiya Y, Imanaka T1998 Nov 69827558
Characterization and directed evolution of BliGO, a novel glycine oxidase from Bacillus licheniformis.Zhang K, Guo Y, Yao P, Lin Y, Kumar A, Liu Z, Wu G, Zhang L2016 Apr26920475
Glyphosate resistance by engineering the flavoenzyme glycine oxidase.Pedotti M, Rosini E, Molla G, Moschetti T, Savino C, Vallone B, Pollegioni L2009 Dec 2519864430
Characterization and structural modeling of a novel thermostable glycine oxidase from Geobacillus kaustophilus HTA426.Martínez-Martínez I, Navarro-Fernández J, García-Carmona F, Takami H, Sánchez-Ferrer A2008 Mar17894345
Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein.Job V, Marcone GL, Pilone MS, Pollegioni L2002 Mar 111744710

RHEA:12472 H2O + N-ethylglycine + O2 = ethylamine + glyoxylate + H2O2
RULE(radius=1) [*:1]-[CH2;+0:2]-[NH;+0:3]-[*:4].[O;H0;+0:5]=[O;H0;+0:6].[OH2;+0:7]>>[*:1]-[CH;+0:2]=[O;H0;+0:7].[*:4]-[NH2;+0:3].[OH;+0:5]-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of a novel glycine oxidase from Bacillus subtilis.Nishiya Y, Imanaka T1998 Nov 69827558
Characterization and directed evolution of BliGO, a novel glycine oxidase from Bacillus licheniformis.Zhang K, Guo Y, Yao P, Lin Y, Kumar A, Liu Z, Wu G, Zhang L2016 Apr26920475
Glyphosate resistance by engineering the flavoenzyme glycine oxidase.Pedotti M, Rosini E, Molla G, Moschetti T, Savino C, Vallone B, Pollegioni L2009 Dec 2519864430
Characterization and structural modeling of a novel thermostable glycine oxidase from Geobacillus kaustophilus HTA426.Martínez-Martínez I, Navarro-Fernández J, García-Carmona F, Takami H, Sánchez-Ferrer A2008 Mar17894345
Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein.Job V, Marcone GL, Pilone MS, Pollegioni L2002 Mar 111744710

RHEA:15165 H2O + O2 + sarcosine = glyoxylate + H2O2 + methylamine
RULE(radius=1) [*:1]-[CH2;+0:2]-[NH;+0:3]-[*:4].[O;H0;+0:5]=[O;H0;+0:6].[OH2;+0:7]>>[*:1]-[CH;+0:2]=[O;H0;+0:7].[*:4]-[NH2;+0:3].[OH;+0:5]-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of a novel glycine oxidase from Bacillus subtilis.Nishiya Y, Imanaka T1998 Nov 69827558
Characterization and directed evolution of BliGO, a novel glycine oxidase from Bacillus licheniformis.Zhang K, Guo Y, Yao P, Lin Y, Kumar A, Liu Z, Wu G, Zhang L2016 Apr26920475
Glyphosate resistance by engineering the flavoenzyme glycine oxidase.Pedotti M, Rosini E, Molla G, Moschetti T, Savino C, Vallone B, Pollegioni L2009 Dec 2519864430
Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein.Job V, Marcone GL, Pilone MS, Pollegioni L2002 Mar 111744710

RHEA:22688 D-alanine + H2O + O2 = H2O2 + NH4(+) + pyruvate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[O;H0;+0:5]=[O;H0;+0:6].[OH2;+0:7]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:7].[NH3;+0:4].[OH;+0:5]-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of a novel glycine oxidase from Bacillus subtilis.Nishiya Y, Imanaka T1998 Nov 69827558
Characterization and directed evolution of BliGO, a novel glycine oxidase from Bacillus licheniformis.Zhang K, Guo Y, Yao P, Lin Y, Kumar A, Liu Z, Wu G, Zhang L2016 Apr26920475
Glyphosate resistance by engineering the flavoenzyme glycine oxidase.Pedotti M, Rosini E, Molla G, Moschetti T, Savino C, Vallone B, Pollegioni L2009 Dec 2519864430
Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein.Job V, Marcone GL, Pilone MS, Pollegioni L2002 Mar 111744710