EC number:1.4.3.22
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.4 Acting on the CH-NH2 group of donors |
| 1.4.3 With oxygen as acceptor |
| ID: | 1.4.3.22 |
|---|---|
| Description: | Diamine oxidase. |
| Alternative Name: |
SSAO. Semicarbazide-sensitive amine oxidase. Histamine deaminase. Histaminase. Diamino oxhydrase. Cu-containing amine oxidase. Copper amine oxidase. CAO. Amine oxidase (copper-containing). Amine oxidase. |
| Cath: | 1.10.405.10; 1.20.5.1360; 3.10.450.40; 3.50.50.60; 3.90.660.10; 2.70.98.20; 3.10.129.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.4.3.22 |
| BRENDA Enzyme Link: | BRENDA 1.4.3.22 |
| KEGG Enzyme Link: | KEGG1.4.3.22 |
| BioCyc Enzyme Link: | BioCyc 1.4.3.22 |
| ExPASy Enzyme Link: | ExPASy1.4.3.22 |
| EC2PDB Enzyme Link: | EC2PDB 1.4.3.22 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.4.3.22 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.4.3.22 |
| IntEnz Enzyme Link: | IntEnz 1.4.3.22 |
| MEDLINE Enzyme Link: | MEDLINE 1.4.3.22 |
| RHEA:25625 | H2O + histamine + O2 = H2O2 + imidazole-4-acetaldehyde + NH4(+) |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[NH2;+0:3].[O;H0;+0:4]=[O;H0;+0:5].[OH2;+0:6]>>[*:1]-[CH;+0:2]=[O;H0;+0:6].[NH3;+0:3].[OH;+0:4]-[OH;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mammalian Cu-containing amine oxidases (CAOs): new methods of analysis, structural relationships, and possible functions. | Houen G | 1999 | 10668504 |
| The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter. | Chassande O, Renard S, Barbry P, Lazdunski M | 1994 May 20 | 8182053 |
| Human placental diamine oxidase. Improved purification and characterization of a copper- and manganese-containing amine oxidase with novel substrate specificity. | Crabbe MJ, Waight RD, Bardsley WG, Barker RW, Kelly ID, Knowles PF | 1976 Jun 1 | 182134 |
| Human kidney diamine oxidase: heterologous expression, purification, and characterization. | Elmore BO, Bollinger JA, Dooley DM | 2002 Jun | 12072962 |