EC number:1.4.3.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.4 Acting on the CH-NH2 group of donors |
| 1.4.3 With oxygen as acceptor |
| ID: | 1.4.3.5 |
|---|---|
| Description: | Pyridoxal 5'-phosphate synthase. |
| Alternative Name: |
Pyridoxine (pyridoxamine)phosphate oxidase. Pyridoxine (pyridoxamine) 5'-phosphate oxidase. Pyridoxamine-phosphate oxidase. Pyridoxamine phosphate oxidase. Pyridoxamine 5'-phosphate oxidase. PMP oxidase. |
| Prosite: | PDOC00815; |
| PDB: |
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| Cath: | 3.20.20.70; 3.30.360.10; 3.40.50.720; 3.40.50.880; 3.40.640.10; 3.90.1150.10; 2.30.110.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.4.3.5 |
| BRENDA Enzyme Link: | BRENDA 1.4.3.5 |
| KEGG Enzyme Link: | KEGG1.4.3.5 |
| BioCyc Enzyme Link: | BioCyc 1.4.3.5 |
| ExPASy Enzyme Link: | ExPASy1.4.3.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.4.3.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.4.3.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.4.3.5 |
| IntEnz Enzyme Link: | IntEnz 1.4.3.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.4.3.5 |
| RHEA:15817 | H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[NH2;+0:3].[O;H0;+0:4]=[O;H0;+0:5].[OH2;+0:6]>>[*:1]-[CH;+0:2]=[O;H0;+0:6].[NH3;+0:3].[OH;+0:4]-[OH;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Expression, purification, and characterization of recombinant Escherichia coli pyridoxine 5'-phosphate oxidase. | Di Salvo M, Yang E, Zhao G, Winkler ME, Schirch V | 1998 Aug | 9693059 |
| Kinetic limitation and cellular amount of pyridoxine (pyridoxamine) 5'-phosphate oxidase of Escherichia coli K-12. | Zhao G, Winkler ME | 1995 Feb | 7860596 |
| Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway. | González E, Danehower D, Daub ME | 2007 Nov | 17873088 |
| Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana. | Sang Y, Barbosa JM, Wu H, Locy RD, Singh NK | 2007 Feb 6 | 17224143 |
| Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase. | di Salvo ML, Ko TP, Musayev FN, Raboni S, Schirch V, Safo MK | 2002 Jan 18 | 11786019 |
| RHEA:15149 | O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[OH;+0:4]-[OH;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Expression, purification, and characterization of recombinant Escherichia coli pyridoxine 5'-phosphate oxidase. | Di Salvo M, Yang E, Zhao G, Winkler ME, Schirch V | 1998 Aug | 9693059 |
| Kinetic limitation and cellular amount of pyridoxine (pyridoxamine) 5'-phosphate oxidase of Escherichia coli K-12. | Zhao G, Winkler ME | 1995 Feb | 7860596 |
| Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity. | Mashalidis EH, Mukherjee T, Sledź P, Matak-Vinković D, Boshoff H, Abell C, Barry CE 3rd | 2011 | 22110704 |
| Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway. | González E, Danehower D, Daub ME | 2007 Nov | 17873088 |
| Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana. | Sang Y, Barbosa JM, Wu H, Locy RD, Singh NK | 2007 Feb 6 | 17224143 |
| Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase. | di Salvo ML, Ko TP, Musayev FN, Raboni S, Schirch V, Safo MK | 2002 Jan 18 | 11786019 |