EC number:1.4.9.2
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.4 Acting on the CH-NH2 group of donors |
| 1.4.9 With a copper protein as acceptor |
| ID: | 1.4.9.2 |
|---|---|
| Description: | Aralkylamine dehydrogenase (azurin). |
| Alternative Name: |
Arylamine dehydrogenase. Aromatic amine dehydrogenase. |
| Cath: | 2.130.10.10; 2.60.30.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.4.9.2 |
| BRENDA Enzyme Link: | BRENDA 1.4.9.2 |
| KEGG Enzyme Link: | KEGG1.4.9.2 |
| BioCyc Enzyme Link: | BioCyc 1.4.9.2 |
| ExPASy Enzyme Link: | ExPASy1.4.9.2 |
| EC2PDB Enzyme Link: | EC2PDB 1.4.9.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.4.9.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.4.9.2 |
| IntEnz Enzyme Link: | IntEnz 1.4.9.2 |
| MEDLINE Enzyme Link: | MEDLINE 1.4.9.2 |
| RHEA:47796 | an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H(+) + NH4(+) + 2 reduced [azurin] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[NH2;+0:3].[Cu+2;H0:4].[Cu+2;H0:5].[OH2;+0:6]>>[*:1]-[CH;+0:2]=[O;H0;+0:6].[Cu+;H0:4].[Cu+;H0:5].[NH3;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification of reaction products and intermediates of aromatic-amine dehydrogenase by 15N and 13C NMR. | Bishop GR, Zhu Z, Whitehead TL, Hicks RP, Davidson VL | 1998 Mar 15 | 9494080 |
| Electron transfer reactions between aromatic amine dehydrogenase and azurin. | Hyun YL, Davidson VL | 1995 Sep 26 | 7547967 |
| Crystallization and properties of aromatic amine dehydrogenase from Pseudomonas sp. | Iwaki M, Yagi T, Horiike K, Saeki Y, Ushijima T, Nozaki M | 1983 Jan | 6830237 |
| Crystal structure of an electron transfer complex between aromatic amine dehydrogenase and azurin from Alcaligenes faecalis. | Sukumar N, Chen ZW, Ferrari D, Merli A, Rossi GL, Bellamy HD, Chistoserdov A, Davidson VL, Mathews FS | 2006 Nov 14 | 17087503 |
| Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis. Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans. | Hothi P, Khadra KA, Combe JP, Leys D, Scrutton NS | 2005 Nov | 16279953 |
| Gated and ungated electron transfer reactions from aromatic amine dehydrogenase to azurin. | Hyun YL, Zhu Z, Davidson VL | 1999 Oct 8 | 10506161 |