Enzyme

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EC Tree
     1. Oxidoreductases
        1.4 Acting on the CH-NH2 group of donors
            1.4.99 With unknown physiological acceptors
ID:1.4.99.5
Description:Glycine dehydrogenase (cyanide-forming).
Alternative Name: Hydrogen cyanide synthase.
HCN synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.4.99.5
BRENDA Enzyme Link: BRENDA 1.4.99.5
KEGG Enzyme Link: KEGG1.4.99.5
BioCyc Enzyme Link: BioCyc 1.4.99.5
ExPASy Enzyme Link: ExPASy1.4.99.5
EC2PDB Enzyme Link: EC2PDB 1.4.99.5
ExplorEnz Enzyme Link: ExplorEnz 1.4.99.5
PRIAM enzyme-specific profiles Link: PRIAM 1.4.99.5
IntEnz Enzyme Link: IntEnz 1.4.99.5
MEDLINE Enzyme Link: MEDLINE 1.4.99.5
MSA:

1.4.99.5;

Phylogenetic Tree:

1.4.99.5;

Uniprot:
M-CSA:
RHEA:15821 2 A + glycine = 2 AH2 + CO2 + hydrogen cyanide
RULE(radius=1) [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH2;+0:4]-[NH2;+0:5]>>[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[CH;+0:4]#[N;H0;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of the hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0.Laville J, Blumer C, Von Schroetter C, Gaia V, Défago G, Keel C, Haas D1998 Jun9620970
Cyanide production from glycine by a homogenate from a Pseudomonas species.Wissing F1975 Feb234422
Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesis.Castric PA1977 May233722
Mechanism, regulation, and ecological role of bacterial cyanide biosynthesis.Blumer C, Haas D2000 Mar10763748