| EC Tree |
| 1. Oxidoreductases |
| 1.4 Acting on the CH-NH2 group of donors |
| 1.4.99 With unknown physiological acceptors |
| ID: | 1.4.99.5 |
|---|---|
| Description: | Glycine dehydrogenase (cyanide-forming). |
| Alternative Name: |
Hydrogen cyanide synthase. HCN synthase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.4.99.5 |
| BRENDA Enzyme Link: | BRENDA 1.4.99.5 |
| KEGG Enzyme Link: | KEGG1.4.99.5 |
| BioCyc Enzyme Link: | BioCyc 1.4.99.5 |
| ExPASy Enzyme Link: | ExPASy1.4.99.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.4.99.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.4.99.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.4.99.5 |
| IntEnz Enzyme Link: | IntEnz 1.4.99.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.4.99.5 |
| RHEA:15821 | 2 A + glycine = 2 AH2 + CO2 + hydrogen cyanide |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH2;+0:4]-[NH2;+0:5]>>[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[CH;+0:4]#[N;H0;+0:5] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of the hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0. | Laville J, Blumer C, Von Schroetter C, Gaia V, Défago G, Keel C, Haas D | 1998 Jun | 9620970 |
| Cyanide production from glycine by a homogenate from a Pseudomonas species. | Wissing F | 1975 Feb | 234422 |
| Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesis. | Castric PA | 1977 May | 233722 |
| Mechanism, regulation, and ecological role of bacterial cyanide biosynthesis. | Blumer C, Haas D | 2000 Mar | 10763748 |