EC number:1.4.99.6
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.4 Acting on the CH-NH2 group of donors |
| 1.4.99 With unknown physiological acceptors |
| ID: | 1.4.99.6 |
|---|---|
| Description: | D-arginine dehydrogenase. |
| Alternative Name: |
D-amino-acid dehydrogenase. |
| Cath: | 3.30.9.10; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.4.99.6 |
| BRENDA Enzyme Link: | BRENDA 1.4.99.6 |
| KEGG Enzyme Link: | KEGG1.4.99.6 |
| BioCyc Enzyme Link: | BioCyc 1.4.99.6 |
| ExPASy Enzyme Link: | ExPASy1.4.99.6 |
| EC2PDB Enzyme Link: | EC2PDB 1.4.99.6 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.4.99.6 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.4.99.6 |
| IntEnz Enzyme Link: | IntEnz 1.4.99.6 |
| MEDLINE Enzyme Link: | MEDLINE 1.4.99.6 |
| RHEA:43572 | A + D-arginine + H2O = 5-guanidino-2-oxopentanoate + AH2 + NH4(+) |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[OH2;+0:5]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:5].[NH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Conformational changes and substrate recognition in Pseudomonas aeruginosa D-arginine dehydrogenase. | Fu G, Yuan H, Li C, Lu CD, Gadda G, Weber IT | 2010 Oct 5 | 20809650 |
| Regulation of the dauBAR operon and characterization of D-amino acid dehydrogenase DauA in arginine and lysine catabolism of Pseudomonas aeruginosa PAO1. | Li C, Yao X, Lu CD | 2010 Jan | 19850617 |
| The fourth arginine catabolic pathway of Pseudomonas aeruginosa. | Jann A, Matsumoto H, Haas D | 1988 Apr | 3141581 |
| Importance of glutamate 87 and the substrate α-amine for the reaction catalyzed by D-arginine dehydrogenase. | Ball J, Bui QV, Gannavaram S, Gadda G | 2015 Feb 15 | 25637657 |
| Insights on the mechanism of amine oxidation catalyzed by D-arginine dehydrogenase through pH and kinetic isotope effects. | Yuan H, Xin Y, Hamelberg D, Gadda G | 2011 Nov 23 | 21999550 |
| Atomic-resolution structure of an N5 flavin adduct in D-arginine dehydrogenase. | Fu G, Yuan H, Wang S, Gadda G, Weber IT | 2011 Jul 26 | 21707047 |
| Steady-state kinetic mechanism and reductive half-reaction of D-arginine dehydrogenase from Pseudomonas aeruginosa. | Yuan H, Fu G, Brooks PT, Weber I, Gadda G | 2010 Nov 9 | 20932054 |
| Arginine racemization by coupled catabolic and anabolic dehydrogenases. | Li C, Lu CD | 2009 Jan 20 | 19139398 |