Enzyme

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EC Tree
     1. Oxidoreductases
        1.5 Acting on the CH-NH group of donors
            1.5.3 With oxygen as acceptor
ID:1.5.3.21
Description:4-methylaminobutanoate oxidase (methylamine-forming).

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.5.3.21
BRENDA Enzyme Link: BRENDA 1.5.3.21
KEGG Enzyme Link: KEGG1.5.3.21
BioCyc Enzyme Link: BioCyc 1.5.3.21
ExPASy Enzyme Link: ExPASy1.5.3.21
EC2PDB Enzyme Link: EC2PDB 1.5.3.21
ExplorEnz Enzyme Link: ExplorEnz 1.5.3.21
PRIAM enzyme-specific profiles Link: PRIAM 1.5.3.21
IntEnz Enzyme Link: IntEnz 1.5.3.21
MEDLINE Enzyme Link: MEDLINE 1.5.3.21
MSA:

1.5.3.21;

Phylogenetic Tree:

1.5.3.21;

Uniprot:
M-CSA:
RHEA:33915 4-(methylamino)butanoate + H2O + O2 = H2O2 + methylamine + succinate semialdehyde
RULE(radius=1) [*:1]-[CH2;+0:2]-[NH;+0:3]-[*:4].[O;H0;+0:5]=[O;H0;+0:6].[OH2;+0:7]>>[*:1]-[CH;+0:2]=[O;H0;+0:7].[*:4]-[NH2;+0:3].[OH;+0:5]-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Final steps in the catabolism of nicotine.Chiribau CB, Mihasan M, Ganas P, Igloi GL, Artenie V, Brandsch R2006 Apr16689938
A novel gamma-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1.Chiribau CB, Sandu C, Fraaije M, Schiltz E, Brandsch R2004 Dec15606755