EC number:1.5.4.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.5 Acting on the CH-NH group of donors |
| 1.5.4 With a disulfide as acceptor |
| ID: | 1.5.4.1 |
|---|---|
| Description: | Pyrimidodiazepine synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.5.4.1 |
| BRENDA Enzyme Link: | BRENDA 1.5.4.1 |
| KEGG Enzyme Link: | KEGG1.5.4.1 |
| BioCyc Enzyme Link: | BioCyc 1.5.4.1 |
| ExPASy Enzyme Link: | ExPASy1.5.4.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.5.4.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.5.4.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.5.4.1 |
| IntEnz Enzyme Link: | IntEnz 1.5.4.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.5.4.1 |
| RHEA:10720 | 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[C;H0;+0:3](-[*:4])=[N;H0;+0:5]-[*:6].[*:7]-[S;H0;+0:8]-[S;H0;+0:9]-[*:10].[OH2;+0:11]>>[*:1]-[CH;+0:2](-[NH;+0:5]-[*:6])-[C;H0;+0:3](-[*:4])=[O;H0;+0:11].[*:7]-[SH;+0:8].[*:10]-[SH;+0:9] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of the enzymes from Drosophila melanogaster that catalyze the conversion of dihydroneopterin triphosphate to the pyrimidodiazepine precursor of the drosopterins. | Wiederrecht GJ, Brown GM | 1984 Nov 25 | 6438092 |
| Identification and characteristics of the structural gene for the Drosophila eye colour mutant sepia, encoding PDA synthase, a member of the omega class glutathione S-transferases. | Kim J, Suh H, Kim S, Kim K, Ahn C, Yim J | 2006 Sep 15 | 16712527 |