EC number:1.5.8.2
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.5 Acting on the CH-NH group of donors |
| 1.5.8 With a flavin or flavoprotein as acceptor |
| ID: | 1.5.8.2 |
|---|---|
| Description: | Trimethylamine dehydrogenase. |
| Alternative Name: |
TMADh. |
| Cath: | 3.20.20.70; 3.40.50.720; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.5.8.2 |
| BRENDA Enzyme Link: | BRENDA 1.5.8.2 |
| KEGG Enzyme Link: | KEGG1.5.8.2 |
| BioCyc Enzyme Link: | BioCyc 1.5.8.2 |
| ExPASy Enzyme Link: | ExPASy1.5.8.2 |
| EC2PDB Enzyme Link: | EC2PDB 1.5.8.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.5.8.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.5.8.2 |
| IntEnz Enzyme Link: | IntEnz 1.5.8.2 |
| MEDLINE Enzyme Link: | MEDLINE 1.5.8.2 |
| RHEA:11864 | H(+) + H2O + oxidized [electron-transfer flavoprotein] + trimethylamine = dimethylamine + formaldehyde + reduced [electron-transfer flavoprotein] |
| RULE(radius=1) | [*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:4].[*:5]-[n;H0;+0:6]1:[*:7]:[*:8]:[n;H0;+0:9]:[c;H0;+0:10](:[*:11])-[c;H0;+0:12]:1:[n;H0;+0:13]:[*:14].[H+;H0:15].[OH2;+0:16]>>[*:5]-[N;H0;+0:6]1-[*:7]:[*:8]-[NH;+0:9]-[c;H0;+0:10](:[*:11]):[c;H0;+0:12]-1:[nH;+0:13]:[*:14].[*:1]-[NH;+0:2]-[*:3].[CH2;+0:4]=[O;H0;+0:16] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The reaction of trimethylamine dehydrogenase with electron transferring flavoprotein. | Huang L, Rohlfs RJ, Hille R | 1995 Oct 13 | 7592591 |
| The purification and properties of a bacterial trimethylamine dehydrogenase. | Colby J, Zatman LJ | 1971 Jan | 5116569 |
| Participation of the iron-sulphur cluster and of the covalently bound coenzyme of trimethylamine dehydrogenase in catalysis. | Steenkamp DJ, Singer TP | 1978 Feb 1 | 204297 |
| Electron transfer and conformational change in complexes of trimethylamine dehydrogenase and electron transferring flavoprotein. | Jones M, Talfournier F, Bobrov A, Grossmann JG, Vekshin N, Sutcliffe MJ, Scrutton NS | 2002 Mar 8 | 11756429 |