EC number:1.5.98.1

Enzyme

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     1. Oxidoreductases
        1.5 Acting on the CH-NH group of donors
            1.5.98 With other, known, physiological acceptors
ID:1.5.98.1
Description:Methylenetetrahydromethanopterin dehydrogenase.
Alternative Name: N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase.
5,10-methylenetetrahydromethanopterin dehydrogenase.
Cath: 1.10.287.1330; 3.40.50.10830;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.5.98.1
BRENDA Enzyme Link: BRENDA 1.5.98.1
KEGG Enzyme Link: KEGG1.5.98.1
BioCyc Enzyme Link: BioCyc 1.5.98.1
ExPASy Enzyme Link: ExPASy1.5.98.1
EC2PDB Enzyme Link: EC2PDB 1.5.98.1
ExplorEnz Enzyme Link: ExplorEnz 1.5.98.1
PRIAM enzyme-specific profiles Link: PRIAM 1.5.98.1
IntEnz Enzyme Link: IntEnz 1.5.98.1
MEDLINE Enzyme Link: MEDLINE 1.5.98.1

EC number:1.5.98.1

MSA:

1.5.98.1;
Phylogenetic Tree:

1.5.98.1;
Uniprot:
M-CSA:
RHEA:16721 5,10-methylenetetrahydromethanopterin + 2 H(+) + oxidized coenzyme F420-(gamma-Glu)(n) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-Glu)(n)
RULE(radius=1) [*:1]-[CH2;+0:2]-[N;H0;+0:3](-[*:4])-[*:5].[*:6]-[n;H0;+0:7]1:[*:8]:[*:9]:[cH;+0:10]:[c;H0;+0:11](:[*:12])-[c;H0;+0:13]:1:[n;H0;+0:14]:[*:15].[H+;H0:16].[H+;H0:17]>>[*:1]-[CH;+0:2]=[N+;H0:3](-[*:4])-[*:5].[*:6]-[N;H0;+0:7]1-[*:8]:[*:9]-[CH2;+0:10]-[c;H0;+0:11](:[*:12]):[c;H0;+0:13]-1:[nH;+0:14]:[*:15]
Reaction
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References

TitleAuthorsDatePubMed ID
Coenzyme F420 dependence of the methylenetetrahydromethanopterin dehydrogenase of Methanobacterium thermoautotrophicum.Hartzell PL, Zvilius G, Escalante-Semerena JC, Donnelly MI1985 Dec 314084309
Purification and properties of 5,10-methylenetetrahydromethanopterin dehydrogenase and 5,10-methylenetetrahydromethanopterin reductase, two coenzyme F420-dependent enzymes, from Methanosarcina barkeri.te Brömmelstroet BW, Geerts WJ, Keltjens JT, van der Drift C, Vogels GD1991 Sep 201911853