EC number:1.6.3.5
| ID: | 1.6.3.5 |
|---|---|
| Description: | Renalase. |
| Alternative Name: |
Alpha-NAD(P)H oxidase/anomerase. |
| Cath: | 3.50.50.60; 3.90.660.10; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.6.3.5 |
| BRENDA Enzyme Link: | BRENDA 1.6.3.5 |
| KEGG Enzyme Link: | KEGG1.6.3.5 |
| BioCyc Enzyme Link: | BioCyc 1.6.3.5 |
| ExPASy Enzyme Link: | ExPASy1.6.3.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.6.3.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.6.3.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.6.3.5 |
| IntEnz Enzyme Link: | IntEnz 1.6.3.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.6.3.5 |
| RHEA:40395 | 1,2-dihydro-beta-NAD + H(+) + O2 = H2O2 + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH2;+0:3]-[C;H0;+0:4](-[*:5])=[CH;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[H+;H0:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[n+;H0:2]1:[cH;+0:8]:[cH;+0:7]:[cH;+0:6]:[c;H0;+0:4](-[*:5]):[cH;+0:3]:1.[OH;+0:10]-[OH;+0:11] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-β-NAD(P) Oxidase Activity from Pseudomonas phaseolicola. | Hoag MR, Roman J, Beaupre BA, Silvaggi NR, Moran GR | 2015 Jun 23 | 26016690 |
| Metabolic function for human renalase: oxidation of isomeric forms of β-NAD(P)H that are inhibitory to primary metabolism. | Beaupre BA, Hoag MR, Roman J, Försterling FH, Moran GR | 2015 Jan 27 | 25531177 |
| Renalase is an α-NAD(P)H oxidase/anomerase. | Beaupre BA, Carmichael BR, Hoag MR, Shah DD, Moran GR | 2013 Sep 18 | 23964689 |
| RHEA:40399 | 1,2-dihydro-beta-NADP + H(+) + O2 = H2O2 + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH2;+0:3]-[C;H0;+0:4](-[*:5])=[CH;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[H+;H0:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[n+;H0:2]1:[cH;+0:8]:[cH;+0:7]:[cH;+0:6]:[c;H0;+0:4](-[*:5]):[cH;+0:3]:1.[OH;+0:10]-[OH;+0:11] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-β-NAD(P) Oxidase Activity from Pseudomonas phaseolicola. | Hoag MR, Roman J, Beaupre BA, Silvaggi NR, Moran GR | 2015 Jun 23 | 26016690 |
| Metabolic function for human renalase: oxidation of isomeric forms of β-NAD(P)H that are inhibitory to primary metabolism. | Beaupre BA, Hoag MR, Roman J, Försterling FH, Moran GR | 2015 Jan 27 | 25531177 |
| Renalase is an α-NAD(P)H oxidase/anomerase. | Beaupre BA, Carmichael BR, Hoag MR, Shah DD, Moran GR | 2013 Sep 18 | 23964689 |
| RHEA:47996 | 1,6-dihydro-beta-NAD + H(+) + O2 = H2O2 + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH2;+0:3]-[CH;+0:4]=[CH;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[H+;H0:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[OH;+0:10]-[OH;+0:11] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-β-NAD(P) Oxidase Activity from Pseudomonas phaseolicola. | Hoag MR, Roman J, Beaupre BA, Silvaggi NR, Moran GR | 2015 Jun 23 | 26016690 |
| Metabolic function for human renalase: oxidation of isomeric forms of β-NAD(P)H that are inhibitory to primary metabolism. | Beaupre BA, Hoag MR, Roman J, Försterling FH, Moran GR | 2015 Jan 27 | 25531177 |
| Renalase is an α-NAD(P)H oxidase/anomerase. | Beaupre BA, Carmichael BR, Hoag MR, Shah DD, Moran GR | 2013 Sep 18 | 23964689 |
| RHEA:48000 | 1,6-dihydro-beta-NADP + H(+) + O2 = H2O2 + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH2;+0:3]-[CH;+0:4]=[CH;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[H+;H0:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[OH;+0:10]-[OH;+0:11] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-β-NAD(P) Oxidase Activity from Pseudomonas phaseolicola. | Hoag MR, Roman J, Beaupre BA, Silvaggi NR, Moran GR | 2015 Jun 23 | 26016690 |
| Metabolic function for human renalase: oxidation of isomeric forms of β-NAD(P)H that are inhibitory to primary metabolism. | Beaupre BA, Hoag MR, Roman J, Försterling FH, Moran GR | 2015 Jan 27 | 25531177 |
| Renalase is an α-NAD(P)H oxidase/anomerase. | Beaupre BA, Carmichael BR, Hoag MR, Shah DD, Moran GR | 2013 Sep 18 | 23964689 |